Results 121 to 130 of about 1,186,802 (304)

A Morphology of Theories of Emergence [PDF]

open access: yes, 2014
“Emergence” – the notion of novel, unpredictable and irreducible properties developing out of complex organisational entities – is itself a complex, multi-dimensional concept.
Tom, Ritchey
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

BAKI–1501 ROMANININ TARİHSEL BOYUTU ÜZERİNE BİR İNCELEME

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2006
Tarihî romanın Azerbaycan edebiyatındaki en önemli temsilcilerinden biri Azize Caferzade’dir. Yazar, tarihî romanlarıile tarihe ışık tutmuşve tarihî olaylarıgünümüze taşımıştır. Bakı-1501, Şah İsmail’in yaşamınıve 16. yüzyıldaki siyasî, toplumsal ve dinî
Sedat Adıgüzel
doaj  

Image of the Samarkand city in the artistic worldview of the historical novel by O. Yoqubov “Treasures of Ulugbek”

open access: yesНеофилология
INTRODUCTION. The purpose of the research is to study the urban text in the reflection of the artistic worldview of the historical novel by Odil Yoqubov “Treasures of Ulugbek”, which allows to consider the work based on the analysis of the place and ...
N. A. Ismatova
doaj   +1 more source

The Impact of Social Capital on Crime: Evidence from the Netherlands [PDF]

open access: yes
This paper investigates the relation between social capital and crime. The analysis contributes to explaining why crime is so heterogeneous across space.
Akçomak, I. Semih, ter Weel, Bas
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

El General en su laberinto de Gabriel García Márquez y Conviene a los felices permanecer en casa de Andrés Hoyos: dos visiones de la Independencia de Colombia

open access: yesHistoria y Sociedad, 2011
The aim of this essay is to compare the political perspectives put forward by two historical novels tackling the theme of Colombia’s Independence: El General en su laberinto (GL) by Gabriel García Márquez, and Conviene a los felices permanecer en casa ...
Gustavo Forero Quintero
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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