Results 111 to 120 of about 10,071,074 (300)

Image of the Samarkand city in the artistic worldview of the historical novel by O. Yoqubov “Treasures of Ulugbek”

open access: yesНеофилология
INTRODUCTION. The purpose of the research is to study the urban text in the reflection of the artistic worldview of the historical novel by Odil Yoqubov “Treasures of Ulugbek”, which allows to consider the work based on the analysis of the place and ...
N. A. Ismatova
doaj   +1 more source

Cache Valley Historical Society P.01

open access: yes, 1950
Official corps of Cache Valley Historical Society include, seated: Mrs. J. S. Stanford, Prof. A. N. Sorensen, David Larson, and Judge Jesse P. Rich. Standing: Taylor Nelson, Prof. Charles J. Sorenson, Dr. S. George Ellsworth, Dr. J. M.

core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

El General en su laberinto de Gabriel García Márquez y Conviene a los felices permanecer en casa de Andrés Hoyos: dos visiones de la Independencia de Colombia

open access: yesHistoria y Sociedad, 2011
The aim of this essay is to compare the political perspectives put forward by two historical novels tackling the theme of Colombia’s Independence: El General en su laberinto (GL) by Gabriel García Márquez, and Conviene a los felices permanecer en casa ...
Gustavo Forero Quintero
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Utah State Historical Society--Annual Dinner, 1959 P.04

open access: yes, 1959
Milton R. Merrill, Vice-President of Utah State University, delivering the main address at the Annual Dinner of the Utah State Historical Society, 1959.
Spencer, Jack
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Türk Denizcilik Tarihi Öğretiminde Kullanılabilecek Romanlar Üzerine Bir Değerlendirme

open access: yesSakarya Üniversitesi Eğitim Fakültesi Dergisi, 2014
Bu çalışmanın amacı Türk denizcilik tarihi öğretiminde kullanılabilecek romanların değerlendirmesini yapmaktır. Bu amaçla literatür taraması yapılmış ilgili romanlar tespit edilmiştir. Çalışmanın yöntemi doküman analizine dayanmaktadır.
Özgür Aktaş
doaj  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

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