Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
INDUSTRIAL TRANSFORMATION IN THE AFTERMATH OF THE CRISIS: An Empirical Analysis of Industrial Policies in France, Germany, Spain and the United Kingdom. CES Open Forum Series 2018-2019, 2019 [PDF]
This paper gauges the forces and structures that shape economic transformation through an analysis of industrial polices in four European economies since the 2008 crisis: France, Germany, Spain and the United Kingdom.
Calvo, Angela Garcia, Coulter, Steve
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
An Examination of Concord Errors in the Academic Writings of Students at a Technical University in Ghana [PDF]
This study explored the teachers’ challenges in using local history projects to develop learners’ historical skills. Despite the importance of local history projects in developing learners’ historical skills and knowledge, there is evidence that teachers
Gifty Serwah Mensah +3 more
doaj +1 more source
Over a century of small hydropower projects in Indonesia: a historical review
Background Hydropower is a mature energy technology and one that could play a more important role in providing clean and reliable energy. In small-scale contexts, hydropower is useful for providing electricity access, balancing intermittent resources ...
Naufal Rospriandana +4 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The restoration of existing structures, especially historical ones, is a complicated endeavour. The often insuffi cient identification of the extant state of a building, the possibility of archaeological fi ndings and the necessary procedures involving ...
Elżbieta Radziszewska-Zielina +5 more
doaj +1 more source
Teachers’ Challenges of Using Local History Projects to Develop Learners’ Historical Skills – A Case Study of Motheo Education District [PDF]
This study explored the teachers’ challenges in using local history projects to develop learners’ historical skills. Despite the importance of local history projects in developing learners’ historical skills and knowledge, there is evidence that teachers
Zwelinjane Mbatha, Boitumelo Moreeng
doaj +1 more source
Historical hydropower projects and demographic processes Case study municipality of Mali Zvornik [PDF]
Construction of dams and creation of artificial water reservoirs affect the transformation of landscape and socioeconomic structure of geospace. Some of the most significant changes are related to demographic processes, manifested by the resettlement of ...
Golić Rajko +2 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source

