Results 61 to 70 of about 1,389,572 (306)

Enhancing data reuse in tunnelling site investigation through transfer learning-based historical data mining

Underground Space
Vast amounts of valuable historical tunnelling site investigation data remain underutilized due to inefficient content-based archiving and searching tools. This study introduces a novel data-driven framework that integrates transfer learning with reverse
Jiawei Xie, Baolin Chen, Shui-Hua Jiang, Hongyu Guo, Si Xie, Jinsong Huang   +5 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

History as an Instrument in the Development of Historical Danish Villages

Buildings, 2016
A central contemporary societal discussion in Denmark concerns settlements that have poor connectivity and are geographically distant to main towns and cities. These settlements are called “outskirts.” Historically significant villages in these outskirts
Morten Birk Jørgensen
doaj   +1 more source

Putting Antarctica on the Map [PDF]

This six-day unit has students examine historical maps of Antarctica and research early explorers to gain perspective on how cartography and our understanding of the globe have changed.

core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Narrativas de histórias: um estudo preliminar na gestão de projetos de Tecnologia da Informação

Ciência da Informação, 2008
Narrativas de histórias é uma técnica de gestão do conhecimento para compartilhamento de experiências, pensamentos e valores no ambiente organizacional.
Valério Brusamolin, Eduardo Amadeu Dutra Moresi   +1 more
doaj  

We're on a roll - Let's keep it going [PDF]

, 2020
The pulse of the CHA is remarkably strong right now. New members have been pouring in, bringing new energy and commitment. Important new projects are unfolding.
Heron, Craig
core   +1 more source

Water infrastructure and social housing in Bogotá: an intersection between modern water management and social housing production [PDF]

, 2016
En la actualidad Bogotá afronta la presión de construir viviendas sociales en ecosistemas frágiles, áreas rurales o zonas propensas a las inundaciones, y al mismo tiempo proteger estas áreas para asegurar la capacidad de resiliencia del medio ambiente.
Rojas Bernal, Claudia Lucia
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Accountability for public sector it projects and the senior responsible owner: a theoretical background and research agenda [PDF]

, 2005
The history of public sector IT capital projects is littered with examples of projects that have been delivered late, or have exceeded their budgets, or have proved unsuitable for their intended use.
Lupson, Jonathan, Partington, David
core