Results 61 to 70 of about 71,035 (266)
Delirium and historical project
Thesis: wissenschaftliche Zeitschrift der Bauhaus-Universität Weimar, vol. 49, 2003, no.
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Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Narrativas de histórias é uma técnica de gestão do conhecimento para compartilhamento de experiências, pensamentos e valores no ambiente organizacional.
Valério Brusamolin, Eduardo Moresi
doaj +1 more source
The Historical Workstation Project : Part 1
Historical Social Research, 16(4), 51 ...
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Enriching Historical Manuscripts: The Bovary Project [PDF]
In this paper we describe the Bovary Project, a manuscripts digitization project of the famous French writer Gustave FLAUBERT's first great work, which should end in 2006 by providing an online access to an hypertextual edition of "Madame Bovary" drafts set.
Nicolas, Stéphane +2 more
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The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
The Chilean Plebiscite: Projections Without Historic Data
Abstract On October 5, 1988, Chileans decided by plebiscite to oust General Pinochet from power and have free presidential elections in 1989. This article describes the projections that the authors made for the results of the plebiscite from early returns.
Engel Goetz, Eduardo +1 more
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We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source

