Results 181 to 190 of about 31,173,191 (303)

Advanced Materials & Methods for Heritage & Archaeology (Second Edition). [PDF]

Materials (Basel)
Calia A, Lettieri M.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

DUDG-SLAM: Dynamic Replay and Depth-Uncertainty-Guided Gaussian SLAM for Robust RGB-D Reconstruction. [PDF]

Sensors (Basel)
Liu J, Zuo T, Tian A, Zhang Y.
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Benefits of childhood vaccines in ecological studies focusing on Germany: a scoping review protocol. [PDF]

BMJ Open
Nolting T, Martin DD.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Reinforcement Learning-Based Temporal Knowledge Graph Reasoning for Predicting Chronic Gastritis Diagnosis and Treatment: Development and Validation Study. [PDF]

JMIR Med Inform
Qu X, Sun Z, Wang Y, Liu H, Yao L, Li D, Song G, Zhang R, Zhang X.   +8 more
europepmc   +1 more source

Historical and biographical papers.

Mode of access: Internet.Collected edition; the parts are first published separately under title "Papers of the Historical Society of Delaware.
Historical Society of Delaware.
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Digital case-library and dual-mentor teaching for medical laboratory science internships in China: a historical comparison educational evaluation. [PDF]

Front Med (Lausanne)
Ding Y, Zhang H, Zhang W, Wang Y, Zhang H, Wu Y, Ma M.   +6 more
europepmc   +1 more source