Results 161 to 170 of about 31,173,191 (303)

Proceedings of the Arizona-Nevada Academy of Science, Volume 20 (1985)

, 1985
TWENTY NINTH ANNUAL MEETING / April 27, 1985 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Participating Societies: Arizona Junior Academy of Science, American Water Resources Association ...
Arizona-Nevada Academy of Science
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Tracing the Roots of Inquiry: A Historical Review of Nursing Research Through Professionalisation Theory. [PDF]

Nurs Inq
Almushawah R, Davis D, Khan E.
europepmc   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 08 (1973)

, 2014
SEVENTEENTH ANNUAL MEETING / May 4-5, 1973 / Participating Societies: Arizona-Nevada Junior Academy of Science, American Water Resources Association / University of Arizona / Tucson, ArizonaThis volume is part of the Arizona-Nevada Academy of Science ...
Arizona-Nevada Academy of Science
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Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Book-embedded hair reveals mineral-rich diets among urban commoners in early modern to modern Japan. [PDF]

Sci Rep
Maruyama A, Kuwaki S, Kimura S, Sanada Y, Oikawa M, Futatsukawa S, Kohmatsu Y, Iriguchi A.   +7 more
europepmc   +1 more source

Letter to members, Kent Historical Society, 2006

, 2006
KENT HISTORICAL SOCIETY September 13, 2006 Dear Friends, Here are some upcoming events of interest to our members. Because many of you have called the Historical Society asking about the future of the Christian Science Church, we want to remind you that ...
Halem, Sandy
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PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 01 (1960)

, 1960
FIRST ANNUAL MEETING / April 9, 1960 / Arizona-Sonora Desert Museum and University of Arizona / Tucson, ArizonaThis volume is part of the Arizona-Nevada Academy of Science collections.
Arizona-Nevada Academy of Science
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Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source