Results 141 to 150 of about 8,692,367 (346)

For the Anniversary of Ruslan Grigorievich Gagkuev

open access: yesОмский научный вестник: Серия "Общество. История. Современность"
The work is a review of the scientific and social activities of the Doctor of Historical Sciences, Chairman of the Board of the Russian Historical Society, Executive Director of the History of the Fatherland Foundation — Ruslan Grigorievich ...
A. V. Sushko
doaj   +1 more source

Towards Good Social Science [PDF]

open access: yes
The paper investigates what is meant by "good science" and "bad science" and how these differ as between the natural (physical and biological) sciences on the one hand and social sciences on the other. We conclude on the basis of historical evidence that
Bruce Edmonds, Scott Moss
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Giacomo Becattini and the Marshall's method. A Schumpeterian approach [PDF]

open access: yes
The studies of Giacomo Becattini concerning the notion of the "Marshallian industrial district" have led a revolution in the field of economic development around the world. The paper offers an interpretation of the methodology adopted by Becattini.
Joan Trullén
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

New Documents for the Biography of the Historian A. H. Slyusarsky (1900/1901–1980).

open access: yesВісник Харківського національного університету імені В.Н. Каразіна. Серія: Ìсторія України. Українознавство: історичні та філософські науки
Research aim. To review and analyse the documents from the postgraduate file of A. H. Sliusarskyi, Doctor of Historical Sciences, Professor, long-time Dean (1947–1962) of the History Department of the O. M. Gorky Kharkiv State University (nowadays – V. N.
Mykhailo Protsenko
doaj   +1 more source

Giacomo Becattini and the notion of “Marshallian Industrial Districtâ€. [PDF]

open access: yes
: The notion of “Marshallian Industrial District†proposed by Giacomo Becattini in the first seventies has led a revolution in the local economic analysis around the world.
Joan Trullen
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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