Results 151 to 160 of about 31,173,191 (303)

Visual perception of landscape renovation in Qinyang's historical and cultural streets: evidence from eye tracking of static streetscape images. [PDF]

Front Psychol
Zhang W, Wang B, Feng L, Wang X, Zhang Y, Qiao L.   +5 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Sample Size Reduction by Applying ML Based Causal Inference Methods. [PDF]

Pharm Stat
Youn A, Han G, Gerard E, Poonia N, Olmos S, Zhang B, Cho M, Houseman A.   +7 more
europepmc   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 23 (1988)

, 1988
THIRTY-SECOND ANNUAL MEETING / April 16, 1988 / Participating Societies - Arizona Junior Academy of Science, American Water Resources Association, Arizona Hydrological Society / University of Arizona / Tucson, ArizonaThis volume is part of the Arizona ...
Arizona-Nevada Academy of Science
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Self-Adapting Priors for Dynamic Borrowing in Three-Arm Non-Inferiority Trials With Pre-Specified Margin. [PDF]

Stat Med
Zhao Y, Yuan Y, Tiwari R, Ghosh S.
europepmc   +1 more source

SPACES OF THE HISTORICAL SCIENCE [PDF]

Vestnik Tomskogo gosudarstvennogo universiteta, 2015
openaire   +1 more source

Proceedings of the Arizona-Nevada Academy of Science, Volume 15 (1980)

, 1979
Twenty-Fourth Annual Meeting of the Arizona-Nevada Academy of Science and the Fifty-Sixth Annual Meeting Southwestern and Rocky Mountain Division American Association for the Advancement of Science / April 9-12, 1980 / Participating Societies: Arizona ...
Arizona-Nevada Academy of Science
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Three-Dimensional Airway Reconstruction and Computational Spray Simulation to Guide Bronchoscopic Amphotericin B Delivery in Chronic Pulmonary Aspergillosis: An Exploratory Prospective Cohort Study With Historical Controls. [PDF]

Mycoses
Cheng Y, Zhu H, Wan G, Chen E, Chen R, Su C, Xu H, Fu X, Kong W, Zhang J.   +9 more
europepmc   +1 more source