Results 171 to 180 of about 426,189 (312)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Kent Historical Society Quarterly Bulletin, Volume 29, December 1997
, 1997 The newsletter of the Kent Historical Society 152 Fra11klin Avenue, P.O. Box 663, Kent. Ohio 44240 - {330) 678-2712 Volume 29 - December 1997 Newsletter Becomes "THE KENTENNIAL" Paula Theophila of Kent was named \\1lllller of the contest to select a name
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Two hundred years of historical spawning and nursery data for coregonine fishes in the Laurentian Great Lakes. [PDF]
Sci DataBrant CO +15 more
europepmc +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
historical introduction to the philosophy of science
, 1980 John Losee.248 p. : ill.
Losee, John.
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From "carbohydrate" to standardized Chinese terminology: historical evolution and implications for nutrition communication. [PDF]
Front NutrZeng S, Zhang H, Miao P.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
WOMEN IN SCIENCE: historical perspectives
, 2015 Traça uma análise crítica sobre o texto Women in science: historical perspectives, capítulo pertencente ao documento Women at work: a meeting on the status of women in astronomy, publicado pelo Space Telescope Science Institute, em 1993 por URRY, C. M.
Hayashi, Carlos Roberto Massao +1 more
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
What if There Were Desktop Access to the Computer Science Literature?
, 1992 What if there was an electronic computer science library? Consider the possibilities of having your favorite publications available within finger's reach.
Fox, Edward A. +5 more
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