Results 131 to 140 of about 31,173,191 (303)

Utah State Historical Society--Annual Dinner, 1959 P.01

open access: yes, 1959
Levi Edgar Young, Governor George D.Clyde and Edward Mabey (receiving post-humous award for his father, Charles R. Mabey) at Historical Society Annual Dinner. Mr. Young and Mr. Mabey were presented with Honorary Life Member Awards. Governor Clyde holding
Spencer, Jack
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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

How It All Came About: History of Manatee Village Historical Park

open access: yes, 1984
Norma Carter and Ken Dierks discuss the creation of the Manatee Village Historical ...
Carter, Norma; Dierks, Ken;
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Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science (1963)

open access: yes, 1963
SEVENTH ANNUAL MEETING / March 30, 1963 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / University of Arizona / Tucson, ArizonaThis volume is part of the Arizona-Nevada Academy of Science collections.
Arizona-Nevada Academy of Science
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Proceedings of the Arizona-Nevada Academy of Science (1966)

open access: yes, 1966
TENTH ANNUAL MEETING / April 2, 1966 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Arizona State University / Tempe, ArizonaThis volume is part of the Arizona-Nevada Academy of Science collections.
Arizona-Nevada Academy of Science
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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