Results 81 to 90 of about 1,885,281 (312)

An Introduction to Topological Insulators [PDF]

, 2013
Electronic bands in crystals are described by an ensemble of Bloch wave functions indexed by momenta defined in the first Brillouin Zone, and their associated energies.
Carpentier, David, Fruchart, Michel
core   +4 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

A arqueologia como paradigma de ciência histórica e interdisciplinar

Estudos Avançados
RESUMO Neste artigo a arqueologia será utilizada como um estudo de caso ilustrando a discussão a respeito das diferentes modalidades de ciência e das diferentes ontologias envolvidas. Argumentamos que a arqueologia é tão interdisciplinar que não pode ser
ASTOLFO GOMES DE MELLO ARAUJO
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Eponyms in medical sciences: historical errors that lead to injustice

Revista de la Facultad de Medicina, 2018
Introduction: Throughout history, eponyms have been used in medical sciences to designate anatomical structures although they do not provide any descriptive or functional information, which is equivalent to a mistake in the light of current thinking ...
Jorge Eduardo Duque-Parra, John Barco-Ríos, Natalia Dávila-Alzate   +2 more
doaj   +1 more source

Tapping Environmental History to Recreate America’s Colonial Hydrology [PDF]

, 2010
To properly remediate, improve, or predict how hydrological systems behave, it is vital to establish their histories. However, modern-style records, assembled from instrumental data and remote sensing platforms, hardly exist back more than a few decades.
Arrigo, Jennifer, Bain, Daniel J., Brandt, Sara, Duncan, Jonathan M., Greco, Francesca, Green, Mark B., Kim, Hyojin, Kumar, Sanjiv, Lally, Michael, Muñoz-Hernandez, Andrea, Parolari, Anthony J., Pastore, Christopher L., Pellerin, Brian, Salant, Nira, Schlosser, Adam, Vörösmarty, Charles J., Zalzal, Kate   +16 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Using Organization Theory to Explore the Changing Role of Medical Libraries [PDF]

, 2012
This historical research review uses organization theory to describe and interpret the evolution of American hospitals, medical libraries, and the role of the professional librarian.
Fatkin, Kathy J
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source