Results 141 to 150 of about 500,244 (291)

Prevalence and risk factors for nephrolithiasis in adults with cystic fibrosis: A retrospective cohort study. [PDF]

PLoS One
Ryoo DY, Ladd N, Culp S, Harris S, Murray G, McGuinness M, Kirkby SE, Shidham G, Rice A, Roberts KM, Papachristou GI, Hart PA, Ramsey ML.   +12 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Photo Quiz: A camper with fever, headache, and fatigue. [PDF]

J Clin Microbiol
von Bredow B, Sims MD, Boyanton BL.
europepmc   +1 more source

The Presbyterian Enterprise; Sources of American Presbyterian History by Maurice W. Armstrong, Lefferts A. Loetscher, and Charles A. Anderson

, 1956
Hugh T. Lefler
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Glucagon-like peptide-1 receptor agonists for obesity: Growing popularity met with growing questions over safety. [PDF]

PLoS Med
Chao AM, Gilden A, Wadden TA.
europepmc   +1 more source

A Study of the Methods of Teaching American History in the Catholic Girls' High Schools in Chicago

, 1931
Agnes Marie Lennon
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Toward a Biocultural Synthesis of the Peopling of the Americas: Introduction to the Special Issue. [PDF]

Am J Biol Anthropol
Menéndez LP, Hubbe M.
europepmc   +1 more source

American Intellectual Histories and Historians by Robert Allen Skotheim

, 1967
Robert D. Marcus
openalex   +1 more source