Results 61 to 70 of about 958,452 (268)

Effectiveness of Case-Based and Project-Based Learning in Promoting Sustainability Awareness: A Comparative Study

open access: yesJournal of Education Technology
History learning, which is still dominated by conventional methods, tends to focus only on the cognitive aspect and has not fully addressed the affective and conative dimensions that are crucial in fostering students’ ecological awareness.
Khusnul Khotimah   +4 more
doaj   +1 more source

A Hypermedia-Supported program and its effect on developing historical reasoning skills among first year secondary school students [PDF]

open access: yesInternational Journal of Instructional Technology and Educational Studies
This study investigated the effect of a hypermedia-supported program on developing historical reasoning skills among first-year secondary school students in Egypt.
kholoud ibrahem, Samia Fayed
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Using Historical Sites in East Kalimantan for Education: Challenges and Opportunities

open access: yesYupa: Historical Studies Journal, 2018
The historical site can be used as a source of learning history, a model of learning history, media history learning, to enhance literacy history or as historical attractions.
Muhammad Azmi
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Taking the perspective of the other seriously? understanding historical argument Levando a sério a perspectiva do outro: compreendendo o argumento histórico

open access: yesEducar em Revista, 2011
This paper discusses the nature of argument and its role and importance in historical learning. The paper describes pedagogic strategies developed to help school pupils understand what argument is, model how arguments work and think about how arguments ...
Arthur Chapman
doaj   +1 more source

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