Results 61 to 70 of about 16,191,908 (309)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Journal of Nonformal EducationBackground: Technological Pedagogical Content Knowledge (TPACK) is a vital framework for integrating technology into education. In Indonesia, TPACK research has grown significantly, yet most studies focus on science and mathematics, leaving gaps in ...
Leo Agung Sutimin +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Cogent Social SciencesThe struggle for belonging in postcolonial nations is often haunted by colonial-era racial hierarchies that continue to shape the boundaries of national identity.
Riyadi, Warto, Sariyatun
doaj +1 more source
Journal of Research in Education Sciences, 2011 近來歷史教育的目標，已逐漸從傳統史實傳遞中鬆綁，走向強化學生歷史思維能力之趨勢。其中，「歷史神入」（historical empathy）與「歷史觀點取替」（historical perspective taking,HPT）乃為一適合應用於中學生歷史思維教學的切入點。本研究參照Hartmann 與Hasselhorn（2008）提出的歷史觀點取替模式為架構，編擬一份適用於國、高中生之歷史觀點取替測驗工具，以高雄市某八年級、九年級學生，以及某高中二年級學生為施測對象，得有效問卷1,017份。研究結果顯示，
楊淑晴 Shu-Ching Yang +1 more
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Überzeugungen von Geschichtslehrpersonen empirisch erforschen.
Österreichische Zeitschrift für Geschichtswissenschaften, 2021 This article deals with a field of empirical history education research, which is currently attracting increased attention within the German-speaking and the international communities – namely history teachers’ beliefs. It is argued that although beliefs
Roland Bernhard
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
, 2023 This article presents the changes in history education that bring school history closer to public history and discusses the potential of a textbook as a tool for fostering public history.
Wojdon, Joanna
core +1 more source