Results 41 to 50 of about 2,099,771 (306)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Recenzja książki Wojciecha Klimczyka «Wirus mobilizacji. Taniec a kształtowanie się nowoczesności (1455–1795)» (Kraków 2015, Universitas)

open access: yesPamiętnik Teatralny, 2018
In his work, Wirus mobilizacji, Wojciech Klimczyk presents a history of Western Europe interpreted through the changing dancing practices, or to use Klimczyk’s own vocabulary, an owerview of subsequent social choreographies.
Grzegorz Kondrasiuk
doaj   +1 more source

Barriers to European bioenergy expansion [PDF]

open access: yes, 2009
The European Commission has set challenging targets for renewable energy expansion in Europe as part of its strategy to limit greenhouse gas emissions.
Prins, Wolter, Thornley, Patricia
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Economic and Historical Foundation of the Common Agricultural Policy in Europe [PDF]

open access: yes
The Common Agricultural Policy (CAP) was founded in the 1950s with price support as the main policy instrument. Despite massive criticism from both within and outside the EU, price support remains the backbone of the CAP.
Zobbe, Henrik
core   +4 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

The sword of god: Plague and episcopal authority in the Late Antique West [PDF]

open access: yes
This thesis examines three major historical figures of Early Medieval Europe to discover the attitudes and responses to the plague: Pope Gregory the Great, Gregory of Tours, and the Venerable Bede.
Kenney, Amanda
core   +1 more source

Czesław Miłosz’ American Experience in Światło dzienne (Daylight) [PDF]

open access: yes, 2016
Miłosz’s volume Światło dzienne (Daylight, 1953) is conventionally read by critics as the political poetry deeply engaged with history. The article offers a corrective to this traditional reading by interpreting the volume as an interplay of European and
Kołodziejczyk, Ewa
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Realising the potential of the family history in risk assessment and primary prevention of coronary heart disease in primary care: ADDFAM study protocol

open access: yesBMC Health Services Research, 2009
Background Coronary heart disease (CHD) is the leading cause of death in the developed world, and its prevention a core activity in current UK general practice.
Kai Joe   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy