Results 61 to 70 of about 13,191,531 (320)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Digital Flipbook Empowerment as A Development Means for History Learning Media

, 2020
The purpose of this research was to help empower the atmosphere and climate of learning students who had different learning styles with the prior generation by using a digital-based instructional media such as digital flipbook.
Muhammad Abror A, Nunuk Suryani, D. Ardianto   +2 more
semanticscholar   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Linfield at 150: Linfield\u27s Faculty Predecessors [PDF]

, 2007
As Linfield College moves into its sesquicentennial year, join Marvin Henberg on a journey exploring how the college has Connected Learning, Life, and Community throughout its ...
Henberg, Marvin, Linfield Magazine Staff
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Strategi Group Investigation untuk Pembelajaran Sejarah di Era Society 5.0: Tantangan dan Solusi

Fajar Historia: Jurnal Ilmu Sejarah dan Pendidikan
Group Investigation is a learning model that is considered appropriate and effective in learning history in the era of society 5.0, but in an era that continues to develop and is fast-paced, the challenges faced in implementing group investigation ...
Muhammad Thoriqun Najah Zain, Aditya Nugroho Widiadi   +1 more
doaj   +1 more source

Open Learning Environment in Early Modern Low Countries History [PDF]

, 2010
This project, part of the individual strand of JISC’s and the Higher Education Academy’s Open Educational Resources pilot programme, will turn a comprehensive survey course in Early Modern Low Countries history, from the late Middle Ages to the end of ...
Tiedau, U
core  

History in schools and the problem of 'the nation' [PDF]

, 2012
The article examines the enduring popularity of a form of school history which is based predominantly on the idea that the transmission of a positive story about the national past will inculcate in young people a sense of loyalty to the state; a ...
Acton, Aldrich, Aldrich, Ball, Ball, Barton, Barton, Blair, Burnham, Burns, Cannadine, Cannadine, Churchwell, Clark, Culpin, Evans, Ferguson, Ferguson, Ferro, Freedland, Gilbert, Gove, Gove, Hake, Hamer, Hamer, Harris, Haydn, Hobsbawn, Howson, Husbands, Joseph, Kelly, Lawlor, Longworth, MacMillan, Maddern, Monbiot, Paton, Patten, Phillips, Price, Rae, Schama, Slater, Starkey, Thomson, Vasagar, Walker, Woodhead, Wooding   +50 more
core   +2 more sources

Managing Diversity in History Learning Based on the Perspective of Kakawin Ramayana

, 2020
This research aims to build a framework of diversity management in history learning based on the reinterpretation of diversity from the perspective of Kakawin Ramayana.

semanticscholar   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source