Results 101 to 110 of about 9,126,145 (305)

Ohio History Center Groundbreaking photographs

, 1966
Governor James Rhodes used an Ohio-shaped shovel to turn the first earth for the new Ohio History Center, shown here on on August 22, 1966. The Ohio Historical Society (now the Ohio History Connection) moved to the new building, located near the Ohio ...
Ohio History Connection
core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Streamline-Based History Matching: A Review [PDF]

, 2016
-In recent years, several methods for streamline-based history matching have been developed. These methods have proved to be efficient for three reasons: First, streamlines delineate flow patterns and can therefore be used to define reduced inverse ...
Lie, Knut-Andreas, Stenerud, Vegard Røine   +1 more
core   +2 more sources

The American Museum of Natural History : its origin, its history, the growth of its departments to December 31, 1909

, 1911
148 p., [12] leaves of plates : ill., col. maps ; 30 cm.2nd edition of History, plan and scope of the American Museum of Natural History, 1910 (https://digitallibrary.amnh.org/handle/2246 ...
Osborn, Henry Fairfield, 1857-1935, American Museum of Natural History., American Museum of Natural History, Osborn, Henry Fairfield, 1857-1935.   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A machine learning framework for rapid forecasting and history matching in unconventional reservoirs. [PDF]

Sci Rep, 2021
Srinivasan S, O'Malley D, Mudunuru MK, Sweeney MR, Hyman JD, Karra S, Frash L, Carey JW, Gross MR, Guthrie GD, Carr T, Li L, Viswanathan HS.   +12 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Ohio History Center Dedication Ceremony photograph

, 1970
This 9.5" x 6.5" (24.13 x 16.51cm) photograph of the dedication of the Ohio History Center, the new home of the Ohio Historical Society (now the Ohio History Connection), was taken on August 23, 1970.
Ohio History Connection
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Putting Context into Schema Matching [PDF]

, 2006
Attribute-level schema matching has proven to be an important first step in developing mappings for data exchange, integration, restructuring and schema evolution. In this paper we investigate contextual schema matching, in which selection conditions are
Elnahrawy, Eiman, Flaster, Michael, Fan, Wenfei; id_orcid, Bohannon, Philip   +3 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source