Results 131 to 140 of about 8,633,749 (309)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Wedding gown and matching petticoat
Wedding gown and matching petticoat (Connecticut, 1780-1790). The gray silk and satin damask dress has a low scoop neck, no darts, pinked three-quarter sleeves that have pierced stars and holes for decoration.
Anne Bissonnette (Photographer)
core
The Principal-Agent Matching Market [PDF]
We propose a model based on competitive markets in order to analyse an economy with several principals and agents. We model the principal-agent economy as a two-sided matching game and characterise the set of stable outcomes of this principal-agent ...
Kaniska Dam
core
, 2015 Codes for density-matching, a new approach for optimization under ...
Pranay Seshadri
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Ohio Historical Center Doughboy statue
, 1970 This statue of a World War I American soldier by sculptor Bruce Wilder Saville sits on the lawn of the Ohio History Center in Columbus, Ohio. Saville, a professor at The Ohio State University, cast the scuplture, named "The Victorius Doughboy" in 1924 to
Ohio History Connection
core
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Assortative Matching and Reputation [PDF]
Consider Becker's classic 1963 matching model, with unobserved fixed types and stochastic publicly observed output. If types are complementary, then matching is assortative in the known Bayesian posteriors (the 'reputations').
Axel Anderson, Lones Smith
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Market Structure and Matching with Contracts [PDF]
Ostrovsky [10] develops a theory of stability for a model of matching in exogenously given networks. For this model a generalization of pairwise stability, chain stability, can always be satisfied as long as agents’ preferences satisfy same side ...
Alexander Westkamp
core