Results 51 to 60 of about 8,633,749 (309)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Putting Context into Schema Matching [PDF]
, 2006 Attribute-level schema matching has proven to be an important first step in developing mappings for data exchange, integration, restructuring and schema evolution. In this paper we investigate contextual schema matching, in which selection conditions are
Elnahrawy, Eiman +3 more
core
Semiglobal Matching Results on the ISPRS Stereo Matching Benchmark [PDF]
, 2011 Digital surface models can be efficiently generated with automatic image matching from optical stereo images. The Working Group 4 of Commission I on "Geometric and Radiometric Modelling of Optical Spaceborne Sensors" provides a matching benchmark ...
Reinartz, Peter +3 more
core +2 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Understanding Tight Naturally Fractured Carbonate Reservoir Architecture for Subsurface Gas Storage
Applied SciencesThis study develops a conceptual framework for characterizing reservoir architecture in multi-component, discrete systems using pressure transient analysis (PTA), aimed at calibrating inflow geometry prior to full-field dynamic simulation for subsurface ...
Sadam Hussain +3 more
doaj +1 more source
A Novel Assisted History Matching Workflow and its Application in a Full Field Reservoir Simulation Model [PDF]
Journal of Petroleum Science and Technology, 2019 The significant increase in using reservoir simulation models poses significant challenges in the design and calibration of models. Moreover, conventional model calibration, history matching, is usually performed using a trial and error process of ...
Mohamed Shams +2 more
doaj +1 more source