Results 61 to 70 of about 238,160 (305)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Generalising history matching for enhanced calibration of computer models [PDF]
, 2021 History matching using Gaussian process emulators is a well-known methodology for the calibration of computer models. It attempts to identify the parts of input parameter space that are likely to result in mismatches between simulator outputs and ...
W Xu (7428281)
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
HISTORY MATCHING WITH SUBSET SIMULATION
International Journal for Uncertainty Quantification, 2021 Gong, Z +3 more
openaire +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
We define the median stable matching for two-sided matching markets with side payments and prove constructively that it exists.
Michael Schwarz, M. Bumin Yenmez
core
Bayesian History Matching Applied to the Calibration of a Gravity Wave Parameterization
Journal of Advances in Modeling Earth SystemsBreaking atmospheric gravity waves (GWs) in the tropical stratosphere are essential in driving the roughly 2‐year oscillation of zonal winds in this region known as the Quasi‐Biennial Oscillation (QBO).
Robert C. King +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Matching with Couples: a Multidisciplinary Survey [PDF]
This survey deals with two-sided matching markets where one set of agents (workers/residents) has to be matched with another set of agents (firms/hospitals). We first give a short overview of a selection of classical results.
Peter Biro, Flip Klijn
core