Results 91 to 100 of about 1,652,481 (345)

Oil Price Shock and Structural Changes in CMEA Trade [PDF]

open access: yes
We analyse trade between countries of the Council of Mutual Economic Assistance in Eastern Europe between 1950 and 1990. Despite central planning and political motivation of the CMEA, we show that trade could be explained by standard demand factors ...
Beckmann, Elisabeth, Fidrmuc, Jarko
core  

Celebrating the nation: the case of Upper Silesia after the plebiscite in 1921 [PDF]

open access: yes, 2008
Book description: The relationship between states, societies, and individuals in Central and Eastern Europe has been characterised by periods of change and redefinition.
Michalczyk, A.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

History of barley (Hordeum vulgare) in Central Europe according to archaeobotanical findings.

open access: yesKvasný průmysl, 2012
This paper describes distribution and use of barley in prehistory and the Early Middle Ages in the context of the development of agriculture and landscape. Study focused on Central Europe, but also other European areas.
Tereza ŠÁLKOVÁ   +3 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Central Banks as Agents of Economic Development [PDF]

open access: yes
In the last two decades, there has been a global sea change in the theory and practice of central banking. The currently dominant “best practice” approach to central banking consists of the following: (1) central bank independence (2) a focus on ...
Gerald Epstein
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Bronzkori tájakon a Benta völgyében : Kutatások a központ és „hátországa” kapcsolatának megismerésére | Bronze Age Landscapes in the Benta Valley : Research on the Hinterland of Bronze Age Centres [PDF]

open access: yes, 2012
Közép-Európában a bronzkori települések hálózatának és a hozzájuk kapcsolódó temetkezéseknek a kutatása a régészeti terepmunkának mindig is meghatározó irányvonalát alkotta.
Czebreszuk, Janusz   +7 more
core  

Simultaneous reconstruction of evolutionary history and epidemiological dynamics from viral sequences with the birth-death SIR model

open access: yes, 2014
The evolution of RNA viruses such as HIV, Hepatitis C and Influenza virus occurs so rapidly that the viruses' genomes contain information on past ecological dynamics.
Drummond, Alexei J.   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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