Results 71 to 80 of about 196,484 (310)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Poland and Poles in the Biography of Carl Gustaf Emil Mannerheim
Journal on European History of Law, 2012 The biography of Marshal of Finland C. G. Mannerheim Poland and the Poles didn’t play important role. Despite this it can be concluded that in the first period of his adult life he had very close contacts with them.
Marek Białokur
doaj
The Nation Should Come First [PDF]
, 2013 By the second half of the 1940s, newly conquered nations of Central and Eastern Europe were expected to adjust multiple professions, including those related to the historical sciences, to the Soviet model.
Górny, Maciej
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
European policies for social inclusion of Roma : Catch 22?
, 2015 The article analyzes contemporary political discourses with regard to social inclusion of Roma on the basis of comparison with achievements and failures in the previous historical period of the communist rule in Eastern Europe.
Elena Marushiakova +4 more
core +1 more source
Starptautiska konference "Diskutablās kolekcijas Centrālajā un Austrumeiropā: koloniālisma un eksotisko etnogrāfisko izrāžu mantojums" 2023. gada 26.–27. oktobris, LU Latvijas vēstures institūts [PDF]
, 2023 Researchers in history, cultural heritage studies, ethnography and anthropology, art and museology, at different stages of their career are gathered in Riga for the international conference co-organized by the Institute of Latvian History, University of ...
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
East Central Europe in the First Globalization (1850-1914)
Studia Historiae Oeconomicae, 2019 The article analyzes the position and the positioning strategy of East Central Europe in the so-called “first globalization (1850-1914)”. The focus is on foreign trade and the transfer of the two most important production factors, i.e. capital and labor.
Uwe Müller
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source