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History Abroad: How Do Denmark and the U.S. Measure Up? [PDF]
, 2014 By viewing bias itself as a product of history, educators and scholars can understand it better in their own times. By studying the historical path of the United States and Denmark, scholars can see that the nature of history can have subtle but ...
Gentilucci, Louis T.
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Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
From Mathematics and Education, to Mathematics Education [PDF]
arXiv, 2016 This chapter takes a historical view of the development of mathematics education, from its initial status as a business mostly managed by mathematicians to the birth of mathematics education as a scientific field of research. Starting from the acknowledgement that research in mathematics education demands more than the traditional focus on discussing ...
arxiv
Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
A history of business education in the junior high school [PDF]
, 1948 Thesis (M.A.)--Boston University, 1948.
Morrissey, Shirley R.
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Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
Pedagogical potential of narrative and life history research in education [PDF]
, 2017 This paper aims to explore and reflect on the pedagogical potential of the narrative and biographical research methodology in education to illuminate and address issues related with immigration, inclusion and social justice.
Herrera Pastor, David, Mancila, Iulia
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