Results 111 to 120 of about 1,200,460 (313)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Uses of History in History Education
, 2016 This compilation thesis contains an introductory chapter and four original articles. The studies comprising this thesis all concern aspects of how historical culture is constituted in historical media and history teachers’ narratives and teaching. It is argued that the teaching of history is a complex matter due to an internal tension resulting from ...
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Public History in Teacher Education [PDF]
Historical knowledge, often overshadowed by mass media communication, plays a crucial role in educating conscious and critical citizens. We want to explore the transformative potential of history in teacher education, particularly through a public ...
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Jacques Attali, Histoires et avenirs de l’éducation
Revue Internationale d’Éducation de Sèvres, 2023 Jean-Pierre Véran
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Looking Ahead : Nordic and British Perspectives on History of Education
From a Nordic and British perspective, the history of education is a vibrant field of knowledge production. It invites scholars from the humanities and social sciences to investigate the continuities and changes in education over time, as well as Bildung,
Göransdotter, Rebecka +1 more
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Editorial: Ripping Yarns [PDF]
, 2017 This is the author accepted manuscript.
Doney, J, Freathy, R
core
The History of Laicism in Turkish Educational History
İlköğretim Online, 2008 The education based upon mores in Turk communities of Middle Asia, started tobecome institutionalized with the adoption of Islam. However, the religious content in education wasintensified during the institutionalization of the scholar system. No significant development took placewith regards to the secularization of education until the renovation ...
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