Results 91 to 100 of about 169,303,448 (355)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

The chemistry of education : a periodic relationship [PDF]

open access: yes, 2003
xiii, 312 leaves ; 28 cm.The purpose and focus of this research is to examine a chemistry of education and to build a metacognitive bridge between the two disciplines, chemistry and education, through autobiographical narrative development of a ...
H-Duke, Michelle   +1 more
core  

CURRENT STATE OF HISTORIC AND EDUCATIONAL RESEARCH

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2013
In this paper we analyze the results of development of national historic and educational research at the turn of the XXth century; pinpoint obvious success and indicate problems and contradictory areas; give grounding to the development model of the XXth
Тимур Альбертович Магсумов
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Hail Mary and holy water : a case study of faith permeation in education [PDF]

open access: yes, 2004
vii, 67 leaves ; 29 cm. --The term "Catholic school" may conjure up images of children praying with fervor to our hallowed Mother on aching knees, or being forgiven all sins with a wave and splash of holy water.
Barretto Rutter, Trudy-Ann   +1 more
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Disability History and Awareness a Resource Guide

open access: yes, 2010
application/pdf; Includes bibliographical and internet references."In May 2009, the Kansas legislature passed Senate Bill No. 41, an act concerning school districts...which required the Kansas State Board of Education to promote recognition of Disability
Kansas. State Department of Education.
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

State Board of Education of Ohio annual report

open access: yes, 2008
Electronic coverage as of Dec.
Ohio. State Board of Education.
core  

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