Results 121 to 130 of about 4,530,314 (306)
“The path of social justice”: A Human Rights History of Social Justice Education [PDF]
Although not often recognized, social justice education in the U.S. is historically and philosophically tied to the twentieth century\u27s human rights initiatives.
Gibson, Melissa L., Grant, Carl A.
core +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Jacques Attali, Histoires et avenirs de l’éducation
Jean-Pierre Véran
doaj +1 more source
The History Major and Undergraduate Liberal Education [PDF]
Argues that the study of history integrates disciplinary knowledge, methods, and principles into a broad education and civic engagement. Recommends that departments set goals for student outcomes, diversify course requirements, and emphasize ...
James Grossman, Stanley N. Katz
core
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
More research is needed into why France’s education system is failing the country’s growing multicultural population [PDF]
France has a history of universal education that stretches back more than a century. However, this system has been marred in recent years by a decrease in student achievement, and recent reforms to address this problem have been less than effective ...
Mattei, Paola
core
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source

