Results 61 to 70 of about 31,708 (242)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Infinite majesty : disabled and athletic métis in David Foster Wallace’s tennis writing [PDF]

open access: yes, 2018
As John Jeremiah Sullivan remarks in his introduction to String Theory, a collection of David Foster Wallace’s essays on tennis, tennis “may be [Wallace’s] most consistent theme at the surface level.” As once an elite junior professional himself, Wallace
Rabe, Michelle Elizabeth
core   +1 more source

Autonomy of the family in the modern world

open access: yesHoryzonty Wychowania, 2017
RESEARCH OBJECTIVE: The purpose of this article is to understand autonomy of the family in the ‘modern’ world by locating the family in the historical changes that led to its present form.
Nidhi Gulati
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

MENTALITIES OF THE ROMANIANS BETWEEN THE TWO WORLD WARS [PDF]

open access: yes
Mentality is defined as an assembly of manners of acting or thinking about someone or something. Related to the history of mentalities in the 19th century the core elements were the building of the nation and the constitutional law and only at the ...
Emilian M. DOBRESCU
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Process Philosophy and the Emergent Theory of Mind: Whitehead, Lloyd Morgan and Schelling [PDF]

open access: yes, 2002
Attempts to ‘naturalize’ phenomenology challenge both traditional phenomenology and traditional approaches to cognitive science. They challenge Edmund Husserl’s rejection of naturalism and his attempt to establish phenomenology as a foundational ...
Gare, Arran
core   +1 more source

Strunt i det!

open access: yesKulturella Perspektiv, 1995
The article is about the difficulties and often the futility in drawing sharp lines between the disciplines of history. The starting point is my own position as economic historian with a strong inclination towards historical psychology and the history ...
Arne Jarrick
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Christendom and Christianity in the Middle Ages: The Relations between Religion, Church, and Society [PDF]

open access: yes, 1995
Reviewed Book: Bredero, Adriaan Hendrik. Christendom and Christianity in the Middle Ages: The Relations between Religion, Church, and Society.
Erb, Peter C.
core   +1 more source

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