Results 41 to 50 of about 317,424 (303)
Photography: Science, Technology, and Practice in Nineteenth-Century Canada
, 2022 Drawing upon empirical research from a larger project on photography in nineteenth-century British North America, this essay proceeds from the conviction that photography—as science, as technology, as practice—warrants closer scrutiny for the ways in ...
Schwartz, Joan M.
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Open Access Emergency Medicine, 2020 Liqaa A Raffee,1 Khaled Z Alawneh,2 Rashid K Ibdah,3 Sukaina I Rawashdeh,3 Sohaib Zoghoul,4 Abdel Salam Ewais,1 Abdel-Hameed Al-Mistarehi5 1Department of Accident and Emergency Medicine, Faculty of Medicine, Jordan University of Science and Technology ...
Raffee LA +6 more
doaj
International Journal of General Medicine, 2021 Nabil Al-Zoubi,1 Nasr Alrabadi,2 Khalid Kheirallah,3 Ahmad Alqudah4 1Department of General Surgery/Vascular Surgery, Jordan University of Science and Technology, Irbid, 22110, Jordan; 2Department of Pharmacology, Faculty of Medicine, Jordan University of
Al-Zoubi N +3 more
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Lychnos, 2017 This article explores the controversy surrounding Swedish veterinary Elis Sandberg and the alternative cancer drug THX from the early 1950’s up until Sandberg’s death in 1989. THX was an extract for injection made from calves’ thymus glands, as Sandberg
Maria Björk
doaj
Environment between System and Nature: Alan Sonfist and the Art of the Cybernetic Environment
communication +1, 2014 This paper examines the role of systems thinking in environmental(ist) art and activism through a close reading and contextualization of Army Ants: Patterns and Structures (1972), an installation by Alan Sonfist, one of the leading figures in U.S.
Etienne Benson
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source