Results 51 to 60 of about 317,424 (303)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Critiquer les sciences et la médecine dans un pays non hégémonique

open access: yesRevue d'anthropologie des connaissances, 2012
The years 1960 and 1970 in many industrialized countries, are times of a large dissent movement on scientific and technological development. Controversies (pesticides, nuclear energy, asbestos) multiply and some groups are questioning radically against ...
Mathieu Quet
doaj   +1 more source

Applying the Publishing Standards of the International Institute of ISO in Persian Journals of History [PDF]

open access: yesتاریخ نگری و تاریخ نگاری, 2019
The Persian journals published in different arenas of science, in printed and electronic versions, follow some special rules and regulations. While the rules for writing and publishing the articles in the Iranian scientific journals are similar in ...
Seyyed mahmood Sadat, Mohammad Jamaloo
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Development of Narrative Practices in Medicine c.1960-c.2000 [PDF]

open access: yes, 2015
‘… if I have to explain to someone, like the anthropologist from Mars, what any of these words like compassion or whatever is, sooner or later I have to tell them a story.’ Professor Arthur Frank Chaired by Professor Brian Hurwitz (King’s College), this ...
JONES, EM
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A consumer study evaluating the extent technology education textbooks use 1993 benchmarks for science literacy [PDF]

open access: yes, 1999
Plan BA review of how well introductory technology education textbooks incorporate the 1993 Benchmarks for Science Literacy were investigated. Important technology education definitions, readability, organization of content and actual substantive ...
Johnson, Douglas Alan
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Opportunities for use of blockchain technology in medicine [PDF]

open access: yes, 2018
Blockchain technology is a decentralized database that stores a registry of assets and transactions across a peer-to-peer computer network, which is secured through cryptography, and over time, its history gets locked in blocks of data that are ...
Radanović, Igor, Likić, Robert
core   +1 more source

Home - About - Disclaimer - Privacy