Results 61 to 70 of about 335,151 (252)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Postdoc - History of Science, Technology and Medicine "Ernst-Haeckel-Haus"

, 2010
Postdoc - History of Science, Technology and Medicine "Ernst-Haeckel-Haus" The Institute for History of Science, Technology and Medicine "Ernst-Haeckel-Haus", Friedrich-Schiller-University, Jena, Germany http://www.ehh.uni-jena.de/ invites applications ...
corpsetmedecine
core  

Acute Basophilic Leukemia Arising from Chronic Myeloid Leukemia with +8, I(17q)(q10) and der(22)t(9;22) After Imatinib Therapy

Journal of Blood Medicine, 2023
Peng Shan,1,2 Hang Dong,1,2 Shilan Li3 1Department of Laboratory, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230036, People’s Republic of China; 2Core Unit ...
Shan P, Dong H, Li S
doaj  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Epilogue: Textiles, Technology, and Gender in China [PDF]

, 2013
The seminal research of Francesca Bray (1997) and Susan Mann (1992, 1997) on women and domestic work, especially textiles, have inspired a generation of new research in cultural history and art history, and the articles presented in this special issue ...
Ko, Dorothy
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A rare presentation of ovarian fibrothecoma in a middle age female: case report

International Journal of Women's Health, 2019
Rawan A Obeidat,1 Abdelwahab J Aleshawi,2 Hasan A Obeidat,2 Samir M Al Bashir3 1Department of Obstetrics & Gynecology, Faculty of Medicine, Jordan University of Science and Technology, Irbid 22110, Jordan; 2Department of General Surgery and Urology,
Obeidat RA, Aleshawi AJ, Obeidat HA, Al Bashir SM   +3 more
doaj  

Socio-Demographic Factors and Other Predictors of Pap Test Uptake Among Women: A Retrospective Study in Ghana

Cancer Management and Research, 2023
Kofi Boamah Mensah,1 Adwoa Bemah Boamah Mensah,2 Peter Yamoah,3 Jennifer Manfo,4 Richmond Amo,5 Ebenezer Wiafe,6 Neelaveni Padayachee,7 Varsha Bangalee8 1Department of Pharmacy Practice, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana ...
Mensah KB, Boamah Mensah AB, Yamoah P, Manfo J, Amo R, Wiafe E, Padayachee N, Bangalee V   +7 more
doaj