Results 111 to 120 of about 5,697,291 (306)
Historians of science and the “Sobel Effect” [PDF]
In 1995, journalist Dava Sobel’s Longitude caused an earthquake in the history of science community. The present article analyses how only recently historians of science have fully realized the novelty the book represented.
Govoni Paola
doaj
History and Science behind the Eating Assessment Tool-10 (Eat-10): Lessons Learned. [PDF]
Schindler A +4 more
europepmc +1 more source
David Stove reviews Selwyn Grave's History of Philosophy in Australia, and praises philosophers for thinking harder about the bases of science, mathematics and medicine than the practitioners in the field. The review is reprinted as an appendix
Stove, D. C.
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Reconstructions: recreating science and technology of the past [PDF]
Historic reconstructions have become a decisive tool in the history of science and technology.
Staubermann, Klaus
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Explanation and Cognition [PDF]
These essays draw on work in the history and philosophy of science, the philosophy of mind and language, the development of concepts in children, conceptual.
Keil, Frank C., Wilson, Robert A.
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Whence philosophy of biology? [PDF]
A consensus exists among contemporary philosophers of biology about the history of their field. According to the received view, mainstream philosophy of science in the 1930s, 40s, and 50s focused on physics and general epistemology, neglecting analyses ...
Byron (formerly Baker), Jason M.
core +1 more source

