Results 61 to 70 of about 1,889,906 (345)
Más allá del positivismo : una interpretación lakatosiana de la enseñanza de las ciencias [PDF]
, 1994 The history of science shows that positivism was the dominant philosophy from about the end of the 19th century to the middle of the 20th century. The main objective of this article is to present a critique of positivist ideas and show how the new ...
Níaz, M.
core +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
L’idée de la « mécanologie » à travers le XXème siècle
Revue d'anthropologie des connaissances, 2022 This article traces the production, reception and circulation of Reflections on the Science of Machines, a book published by French engineer Jacques Lafitte in 1932.
Ghislain Thibault
doaj +1 more source
Nursing redefined: emergent insights from studying the art and science of nursing in Germany and Switzerland. [PDF]
, 2005 Developments in the Art and Science of Nursing is one module of a Masters degree course organised by Cardiff University, Wales, and taught since the year 2003 in Bavaria, Germany.
Biley, Francis
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Arsen Richynsky "Hygiene course of health sciences": history of the publication and main ideas
Journal of Education, Health and Sport, 2020 The article analyzes the work of the well-known socio-political, cultural and educational figure of Ukraineof the first half of the XX century, Arsen Richynsky "Hygiene course of health science", which has not lost its relevance today. The issue of organization of hygienic education and training of students in Ukrainian schools and gymnasiums of the ...
openaire +3 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Focus: new perspectives on science and the Cold War. Introduction.
Isis; an international review devoted to the history of science and its cultural influences, 2010 Twenty years after the fall of the Berlin Wall, the Cold War looks ever more like a slice of history rather than a contemporary reality. During those same twenty years, scholarship on science, technology, and the state during the Cold War era has ...
Hunter Heyck, D. Kaiser
semanticscholar +1 more source
A Textbook Case Revisited. Knowledge as mode of existence [PDF]
, 2007 The paper starts by a visit to an exhibit at the Natural History Museum in New York which shows in parallel series of fossils of horse evolution and series of how paleontologists have varied in their reconstruction of this evolution.
Latour, Bruno
core +1 more source