Results 71 to 80 of about 1,166 (212)
Frontiers in Public HealthIntroductionType 2 diabetes (T2DM) requires sustained behavioral changes to achieve glycemic control (GC) and prevent complications. Social support (SS) is key for self-care in chronic conditions, yet its impact on GC in low-resource settings remains ...
Marta Puig-García +11 more
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RUNNING DETAILS ON THE TWO MOVEMENTS IN THE INTELLECTUAL HISTORY OF SCIENCE AND IDEAS [PDF]
Journal of Baltic Science Education, 2016 A long tradition concerning the causes of the planetary movements existed as to the movements on the earth: the so called problem de motu locali. Starting from late middle Ages many criticisms were carried out against the Aristotelian doctrine of natural and violent motions.
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
173:poster Towards all-inclusive healthcare allocations
BMJ Global Health, 2022 Aksel Braanen Sterri, Albert Didriksen
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The Pearly Gates of the Central Sun
Journal of Interdisciplinary History of IdeasThe history of the relations that have obtained between science and religion—chiefly Western, Catholic and Protestant, Christianity—has attracted considerable attention.
William Francis Ward
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[History of ideas, history of social sciences, and the sociology of knowledge].
Historia, ciencias, saude--Manguinhos, 2018 This article seeks to determine the mutual influence between the sociology of knowledge and the history of ideas within the history of the social sciences. In addition, it intends to outline a preliminary research program for the area in question which integrates relevant contributions from the social sciences and history to contribute to the dialog ...
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source