Results 71 to 80 of about 1,694,874 (301)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Northern Entrepreneur\u27s Counterfeiting of Confederate Currency and The Impact It Had On Inflation [PDF]
, 2018 This thesis, Northern Entrepreneur\u27s Counterfeiting of Confederate Currency and The Impact It Had On Inflation takes an in depth look at the history of counterfeiting the currency of the Confederate States of America during the Civil War by ...
Rector, Raymond
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Scientific ReportsThe Mediterranean fruit fly (Ceratitis capitata) is a globally invasive species and an economically significant pest of fruit crops. Understanding the evolutionary history and local climatic adaptation of this species is crucial for developing effective ...
Pablo Deschepper +10 more
doaj +1 more source
, 2014 The origins of phenotypic variation within mimetic Heliconius butterflies have long fascinated biologists and naturalists. However, the evolutionary processes that have generated this extraordinary diversity remain puzzling. Here we examine intraspecific
Arias, Carlos F. +6 more
core +2 more sources
Contrasting stress fields on correlating margins of the South Atlantic [PDF]
, 2015 The “passiveness” of passive continental margins across the globe is currently under debate since several studies have shown that these margins may experience a variety of stress states and undergo significant vertical movement post-breakup.
Glasmacher, Ulrich Anton +4 more
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Cromohs: Cyber Review of Modern HistoriographyReview of Cátia A.P. Antunes, ed., Pursuing Empire: Brazilians, the Dutch and the Portuguese in Brazil and the South Atlantic, c.1620-1660, Leiden: Brill, 2022, reviewed by Stuart B ...
Stuart B. Schwartz
doaj +1 more source
Gilles de la Tourette Syndrome—A Case Report from Guyana in South America
Behavioural Neurology, 1992 A case of the Gilles de la Tourette syndrome from Guyana in South America is presented. The patient had a positive family history as well as coprolalia, echolalia, and attention deficit disorder with hyperactivity.
V. Eapen, M. M. Robertson
doaj +1 more source