Connexin 43‐Enriched Vesicles Improve Synchronization in hiPSC‐Derived Cardiomyocytes
Plasma membrane‐derived Connectosomes enriched in connexin‐43 are produced from donor hiPSCs and applied to hiPSC‐derived cardiomyocytes (hiPSC‐CMs). Connexin‐43 channels on Connectosomes remain functional, strengthening intercellular electrochemical coupling and increasing network synchronization over time.
Nima Momtahan +8 more
wiley +1 more source
Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng +18 more
wiley +1 more source
Protecting evolution : How to prepare for attacks against the teaching of evolution. [PDF]
Cohen JI.
europepmc +1 more source
The text addresses difficulties for teaching History, the relationship of History teachers with pedagogy and the historical evolution of this relationship, from the imperial period to the present day.
openaire +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
Approach to an Initial Oncologic Patient Encounter: A Simulation-Based Training for First-Year Medical Students. [PDF]
Barcena AJR +8 more
europepmc +1 more source
Bioinspired Adaptive Leg‐Claw Enables Robust Perching and Grasping for UAVs
Inspired by owl limb morphology and bat roosting behavior, this study presents a bioinspired adaptive leg‐claw mechanism that enables UAVs to perform robust and versatile perching and grasping. The design integrates a four‐link tibial structure, tension‐driven deformable feet, and active control, enabling stable perching on various branches and ...
Tianyu Cheng +6 more
wiley +1 more source
Sociodemographic and Clinical Determinants of Glaucoma in a Sub-Saharan African Population: A Case-Control Study. [PDF]
Ampong A +8 more
europepmc +1 more source
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv +11 more
wiley +1 more source
Visualizing pathology: The development of a narrated video autopsy for medical students. [PDF]
Wraith C, Osborn M, Meeran K, Sam AH.
europepmc +1 more source

