Results 11 to 20 of about 2,028,215 (291)

Small molecule-nanobody conjugate induced proximity controls intracellular processes and modulates endogenous unligandable targets

open access: yesNature Communications, 2023
Induced proximity can be used to control diverse cellular processes. Here, the authors develop nanobody-based proximity inducers called SNACIPs, which can be used to regulate either tagged or endogenous proteins, and demonstrate their use in blocking ...
Xiaofeng Sun   +3 more
doaj   +1 more source

Reviewing the Effect of the Stretch-Shortening Cycle Workouts on Shot Hit Performance

open access: yesPhysical Education of Students, 2018
The purpose of this study was to determine the effect of the stretch-shortening workouts for male football players between the ages of 18 and 20 on shot hit performance.
D. Demirci   +4 more
doaj   +1 more source

Efficacy of a four-week uphill sprint training intervention in field hockey players [PDF]

open access: yes, 2016
Current evidence increasingly suggests that very short, supra-maximal bouts of exercise can have significant health and performance benefits. The majority of research conducted in the area however, uses laboratory-based protocols, which can lack ...
Babraj, John A.   +2 more
core   +3 more sources

New platelet functional method for identification of pathogenic antibodies in HIT patients

open access: yesPlatelets, 2017
Heparin-induced thrombocytopenia (HIT) is a thrombotic complication of heparin therapy. The most used functional method for HIT diagnosis is serotonin release assay (SRA).
M. L. Guarino   +6 more
doaj   +1 more source

A felismerésre bemutatás és a hit

open access: yesBelügyi Szemle, 2018
Péter-Simon magabiztos, tiszta, Krisztust felismerő, kiválasztó képességét aligha várhatjuk napjaink adat-, információ- és ingerhalmazoktól terhes világában a bűncselekmények sértettjeitől, tanúitól.
Csaba Fenyvesi
doaj   +1 more source

Fast Freenet: Improving Freenet Performance by Preferential Partition Routing and File Mesh Propagation [PDF]

open access: yes, 2006
The Freenet Peer-to-Peer network is doing a good job in providing anonymity to the users. But the performance of the network in terms of download speed and request hit ratio is not that good.
Ayani, Rassul   +3 more
core   +3 more sources

The compatibility of polylactic acid and polybutylene succinate blends by molecular and mesoscopic dynamics

open access: yesInternational Journal of Smart and Nano Materials, 2020
The compatibility of polylactic acid (PLA)/polybutylene succinate (PBS) blends was studied by molecular dynamics and mesoscopic dynamics, which is a controversial issue in experiments.
Cheng Lin   +3 more
doaj   +1 more source

Red-Light-Activatable AND-Gated Antitumor Immunosuppressant

open access: yesCells, 2023
Immunosuppressants are emerging as promising candidates for cancer therapy with lower cytotoxicity compared to traditional chemotherapy drugs; yet, the intrinsic side effects such as immunosuppression remain a critical concern.
Ziqi Zhou, Yan Zhang, Simin Xia, Xi Chen
doaj   +1 more source

The two-hit theory hits 50

open access: yesMolecular Biology of the Cell, 2021
Few ideas in cancer genetics have been as influential as the “two-hit” theory of tumor suppressors. This idea was introduced in 1971 by Al Knudson in a paper in the Proceedings of the National Academy of Science and forms the basis for our current understanding of the role of mutations in cancer.
openaire   +3 more sources

Research on Digital Meter Reading Method of Inspection Robot Based on Deep Learning

open access: yesApplied Sciences, 2023
Aiming at solving the issue of blurred images and difficult recognition of digital meters encountered by inspection robots in the inspection process, this paper proposes a deep-learning-based method for blurred image restoration and LED digital ...
Wenwei Lin   +4 more
doaj   +1 more source

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