Results 31 to 40 of about 2,028,215 (291)

A comparison of extremal optimization with flat-histogram dynamics for finding spin-glass ground states

open access: yes, 2002
We compare the performance of extremal optimization (EO), flat-histogram and equal-hit algorithms for finding spin-glass ground states. The first-passage-times to a ground state are computed. At optimal parameter of tau=1.15, EO outperforms other methods
Bak P.   +27 more
core   +1 more source

Theory progress and applications of dielectric elastomers

open access: yesInternational Journal of Smart and Nano Materials, 2013
This paper summarizes the research progress of dielectric elastomer (DE) and its composite materials, including the introduction of materials, theoretical research development, and typical applications.
Liwu Liu, Yanju Liu, Jinsong Leng
doaj   +1 more source

A perspective on the discovery of enzyme activators

open access: yesSLAS Discovery, 2022
Enzyme activation remains a largely under-represented and poorly exploited area of drug discovery despite some key literature examples of the successful application of enzyme activators by various mechanisms and their importance in a wide range of ...
Antonia Turberville   +4 more
doaj   +1 more source

Hadron energy response of the Iron Calorimeter detector at the India-based Neutrino Observatory [PDF]

open access: yes, 2013
The results of a Monte Carlo simulation study of the hadron energy response for the magnetized Iron CALorimeter detector, ICAL, proposed to be located at the India-based Neutrino Observatory (INO) is presented.
Choubey, Sandhya   +9 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Preliminary design and analysis of a cubic deployable support structure based on shape memory polymer composite

open access: yesInternational Journal of Smart and Nano Materials, 2016
The deployable structures based on shape memory polymer composites (SMPCs) have been developed for its unique properties, such as high reliability, low-cost, lightweight, and self-deployment without complex mechanical devices compared with traditional ...
Fengfeng Li   +6 more
doaj   +1 more source

Design and motion analysis of a frog-like jumping robot based on a soft body detonation drive

open access: yesMaterials & Design, 2023
Inspired by the instantaneous power of the hindlimbs of frogs and the dexterous posture adjustment of their forelimbs, a frog-like jumping robot based on a soft body detonation drive was designed. By combining the flexibility of silicone material and the
Yitao Pan   +5 more
doaj   +1 more source

Fate of the runner in hit-and-run collisions [PDF]

open access: yes, 2019
In similar-sized planetary collisions, a significant part of the impactor often misses the target and continues downrange. We follow the dynamical evolution of "runners" from giant impacts to determine their ultimate fate. Surprisingly, runners re-impact
Asphaug, Erik, Emsenhuber, Alexandre
core   +2 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

AiZynthFinder: a fast, robust and flexible open-source software for retrosynthetic planning

open access: yesJournal of Cheminformatics, 2020
We present the open-source AiZynthFinder software that can be readily used in retrosynthetic planning. The algorithm is based on a Monte Carlo tree search that recursively breaks down a molecule to purchasable precursors.
Samuel Genheden   +5 more
doaj   +1 more source

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