Results 51 to 60 of about 440,240 (309)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Public Participation as a Tool for Preserving the Environment [PDF]
E3S Web of Conferences, 2019 Environmental Education is the key for creating a clean energy future for not only the nation, but the world. World Energy Consumption relies heavily on coal, oil, and natural gas.
Friman Hen +3 more
doaj +1 more source
Design and research of soft-body cavity-type detonation drivers
iScience, 2023 Summary: According to the high-energy-density movement characteristics of animals during jumping, soft-body cavity-type detonation driver that combines the explosive chemical reaction mechanism of hydrogen and oxygen is designed, in order to control the ...
Yitao Pan +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Reframing innovation and technology for healthcare: A commitment to the human experience
Patient Experience Journal, 2019 This latest special issue of Patient Experience Journal focuses on the role of technology and innovation in patient experience. The articles included in this issue help us think about the ideas of innovation and health information technology (HIT) in ...
Jason Wolf
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A new design tool for feature extraction in noisy images based on grayscale hit-or-miss transforms
, 2011 The Hit-or-Miss transform (HMT) is a well known morphological transform capable of identifying features in digital images. When image features contain noise, texture or some other distortion, the HMT may fail. Various researchers have extended the HMT in
Murray, Paul +5 more
core +1 more source
Health information technology: A key ingredient of the patient experience
Patient Experience Journal, 2015 In this exploration to understand the linkages of health information technology (HIT) and patient experience, a comprehensive literature search was conducted using the key words, “information technology, HIT, patient experience, patient satisfaction, and
Matthew Werder
doaj
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling
Nature Communications, 2022 aGPCRs play key roles in multiple physiological processes. Here the authors report cryo-EM structures of GPR110 in complexes with Gq, Gs, Gi, G12 and G13 protein to reveal a detailed mechanism of aGPCR activation via the tethered stalk peptide and ...
Xinyan Zhu +11 more
doaj +1 more source