Results 81 to 90 of about 2,017,079 (263)
Few ideas in cancer genetics have been as influential as the “two-hit” theory of tumor suppressors. This idea was introduced in 1971 by Al Knudson in a paper in the Proceedings of the National Academy of Science and forms the basis for our current understanding of the role of mutations in cancer.
openaire +3 more sources
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Patient Experience Journal (PXJ) is excited to announce the call for submissions for its July 2019 special issue on the topic of the role of technology in patient & family experience.
Patient Experience Journal
doaj
Cardiac arrhythmia is associated with abnormal electrical activities of the heart, which can be reflected by altered characteristics of electrocardiogram (ECG).
Runnan He +6 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
State Trading and Economic Warfare [PDF]
This report is a study if a multi linear regression could be used to predict the cap hit of hockey forwards from the NHL. Data was collected during the 2010-2011, 2011-2012, and 2012-2013 seasons.
Flogvall, Carl, Nordenskjöld, Stefan
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Research on automatic spraying of single-walled carbon nanotubes and detection of spraying effects
Single-walled carbon nanotubes (SWNTs) have been introduced as compliant electrodes for dielectric elastomers (DEs) due to fault tolerance. To acquire a better electrostrictive strain and longer lifetime, it is essential to obtain a certain and uniform ...
Jianwen Zhao +4 more
doaj +1 more source
Virtual Reality Rhythm Game [PDF]
Virtual reality headsets such as the HTC Vive and Oculus Rift bring robust virtual reality technology in the hands of consumers. However, virtual reality technology is still a very new and unexplored domain with a dearth of compelling software that takes
Lai, Jordan, Yi, Joshua
core +1 more source

