Results 81 to 90 of about 498,175 (297)

HIT-ISOseq paper

open access: yes
HIT-ISOseq paper Supplementary Data and relevant ...
zhuoxing shi (18451083)
core   +1 more source

A hit és az egészség összefüggésének vizsgálata

open access: yes, 2020
Szakdolgozatomban a hit és egészség összefüggésének vizsgálatával foglalkozom. Egyre több tudományos kutatás bizonyítja, azt a tényt, hogy igenis létezik egy kapcsolat a hit és az egészség, a lélek és a test között.
Endreffy, Mária
core  

Tettere studentoppfølging? : undervegsrapport fra et HiT-internt prosjekt [PDF]

open access: yes, 2004
Kvalitetsreformen i høyere utdanning har krav om tettere oppfølging av studentene, men sier ikke så mye om hvordan dette skal kunne gjennomføres i praksis, f.eks. i et emne med mer enn 150 aktive studenter og én (1) foreleser/undervisningsperson. I dette
Istad, Roy M.
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

[News Clip: Hit-run accident]

open access: yes, 1959
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about a fatal hit-and-run accident in ...
WBAP-TV (Television station : Fort Worth, Tex.)
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A hit és a turizmus kapcsolatának vizsgálata Szabolcs-Szatmár-Bereg megye vallási kirándulói körében

open access: yes, 2020
Dolgozatomban a hit és a turizmus kapcsolatát vizsgálom Szabolcs-Szatmár-Bereg megye vallási kirándulói körében. Bemutatom a vallási turizmust és kialakulását, a legismertebb kegyhelyeket Magyarországon és külföldön.
Zatykó Ferencné Csépke, Ildikó
core  

Projekt HIT – Hrvatski iseljenički tisak [PDF]

open access: yes, 2021
Projekt HIT – Hrvatski iseljenički tisak (u daljnjem tekstu Projekt HIT) pokrenut je na Odsjeku za informacijske i komunikacijske znanosti Filozofskoga fakulteta Sveučilišta u Zagrebu 2018. godine.
Barbarić, Ana
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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