Results 81 to 90 of about 2,028,215 (291)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
IEEE Access, 2019 Cardiac arrhythmia is associated with abnormal electrical activities of the heart, which can be reflected by altered characteristics of electrocardiogram (ECG).
Runnan He +6 more
doaj +1 more source
Go-With-The-Winner: Client-Side Server Selection for Content Delivery [PDF]
, 2016 Content delivery networks deliver much of the web and video content in the world by deploying a large distributed network of servers. We model and analyze a simple paradigm for client-side server selection that is commonly used in practice where each ...
Liu, Chang +2 more
core
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Lessons From a Health Information Technology Demonstration in New York Nursing Homes [PDF]
, 2010 Outlines the New York State Nursing Home Health Information Technology Demonstration Project; variations in organizational aims in adopting HIT, perceived or real effects, and resulting quality improvement efforts; and considerations for ...
Scott White, Shana Lieberman Klinger
core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Research on automatic spraying of single-walled carbon nanotubes and detection of spraying effects
International Journal of Smart and Nano Materials, 2014 Single-walled carbon nanotubes (SWNTs) have been introduced as compliant electrodes for dielectric elastomers (DEs) due to fault tolerance. To acquire a better electrostrictive strain and longer lifetime, it is essential to obtain a certain and uniform ...
Jianwen Zhao +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source