Results 121 to 130 of about 25,225,361 (379)

Super‐Resolution Microscopy in Tissue Engineering

Advanced Materials Interfaces, EarlyView.
Super‐resolution microscopy (SRM) has advanced tissue engineering by providing nanoscale insights into cellular interactions. It reveals detailed cell membrane structures, tracks vesicle and virus entry, and visualizes the cytoskeleton. SRM also improves understanding of cell migration, facilitating tissue regeneration, vascularization, immune ...
Navid Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +2 more
wiley   +1 more source

Cytopathic Mechanisms of HIV-1 [PDF]

Virology Journal, 2007
The human immunodeficiency virus type 1 (HIV-1) has been intensely investigated since its discovery in 1983 as the cause of acquired immune deficiency syndrome (AIDS). With relatively few proteins made by the virus, it is able to accomplish many tasks, with each protein serving multiple functions.
openaire   +4 more sources

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Mapping Transmission Dynamics and Drug Resistance Surveillance in the Cyprus HIV-1 Epidemic (2017–2021)

Viruses
The human immunodeficiency virus type 1 (HIV-1) epidemic has been a major public health threat on a global scale since the early 1980s. Despite the introduction of combination antiretroviral therapy (cART), the incidence of new HIV-1 infections continues
Cicek Topcu, Bram Vrancken, Johana Hezka Rodosthenous, David van de Vijver, Georgios Siakallis, Philippe Lemey, Leondios G. Kostrikis   +6 more
doaj   +1 more source

A novel quantitative approach for measuring the reservoir of latent HIV-1 proviruses

Nature, 2019
A stable latent reservoir for HIV-1 in resting CD4+ T cells is the principal barrier to a cure1–3. Curative strategies that target the reservoir are being tested4,5 and require accurate, scalable reservoir assays.
Katherine M. Bruner, Z. Wang, F. Simonetti, A. Bender, K. J. Kwon, Srona Sengupta, E. Fray, Subul A. Beg, A. Antar, K. Jenike, Lynn N. Bertagnolli, A. Capoferri, J. Kufera, Andrew E Timmons, Christopher L. Nobles, J. Gregg, N. Wada, Y. Ho, Hao Zhang, J. Margolick, J. Blankson, S. Deeks, F. Bushman, J. Siliciano, G. Laird, R. Siliciano   +25 more
semanticscholar   +1 more source

Structural Insights From HIV-Antibody Co-Evolution And Related Immunization Studies [PDF]

, 2018
Human immunodeficiency virus type 1 (HIV-1) is a rapidly evolving pathogen and causes the acquired immunodeficiency syndrome (AIDS) in humans. There are ~30-35 million people infected with HIV around the world, and ~25 million have died since the first ...
Fera, Daniela, Morriss, Julia W., , \u2719, Nguyen, Diep, , \u2719, Ton, Therese, , \u2719, Zhou, Jeffrey O., , \u2719   +4 more
core   +1 more source

Thioether Synthesis via the Nickel‐Catalyzed Electrochemical Cross Electrophile Coupling of Aryl/Alkyl Disulfides and Aryl/Alkyl Halides

Advanced Synthesis &Catalysis, EarlyView.
A nickel catalyzed electrochemical cross‐electrophile coupling approach for the base‐free synthesis of (un)symmetric (hetero)aryl and alkyl sulfides from organic halides and disulfides is described. The reaction is broadly applicable and tolerates water and air atmosphere. A formal cross‐electrophile coupling approach enables the base‐free synthesis of
Jona Queder, Gerhard Hilt
wiley   +1 more source

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source

EpiMolBio: A novel user-friendly bioinformatic program for genetic variability analysis

Computational and Structural Biotechnology Journal
Purpose: Genetic sequence analysis has become essential in many fields of medicine, biology, and epidemiology. However, the currently available tools can pose a challenge for users without advanced computational skills.
Roberto Reinosa, Paloma Troyano-Hernáez, Ana Valadés-Alcaraz, África Holguín   +3 more
doaj   +1 more source

Genetic Diversity and Acquired Drug Resistance Mutations Detected by Deep Sequencing in Virologic Failures among Antiretroviral Treatment Experienced Human Immunodeficiency Virus-1 Patients in a Pastoralist Region of Ethiopia

Infection and Drug Resistance, 2021
Erdaw Tachbele,1,2 Samuel Kyobe,3 Fred Ashaba Katabazi,3 Edgar Kigozi,3 Savannah Mwesigwa,3 Moses Joloba,3 Alebachew Messele,1 Wondwossen Amogne,2 Mengistu Legesse,1 Rembert Pieper,4 Gobena Ameni1 1Aklilu Lemma Institute of Pathobiology, Addis Ababa ...
Tachbele E, Kyobe S, Katabazi FA, Kigozi E, Mwesigwa S, Joloba M, Messele A, Amogne W, Legesse M, Pieper R, Ameni G   +10 more
doaj