Results 131 to 140 of about 658,368 (320)
Cell, 2008 RNA interference holds great promise for antiviral therapy, but delivering effective quantities of small interfering RNAs (siRNAs) into the right target cells in vivo represents a major challenge. Kumar et al. (2008) now report a technique to target siRNAs specifically to T cells to suppress viral infection in a humanized mouse model of HIV/AIDS.
openaire +2 more sources
Aggregate, EarlyView.Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai +6 more
wiley +1 more source
The Pan African Medical Journal, 2013 In order to provide preliminary information on the association between cumulative HPV-infection and HIV-1infection, we assayed serum IgG antibodies to HPV in 63 HIV-1 infected adults and 26 apparently healthy HIV-negative adults in Zaria, Northern ...
Dimie Ogoina +2 more
doaj +1 more source
Tumor necrosis factor stimulates transcription of HIV-1 in human T lymphocytes, independently and synergistically with mitogens. [PDF]
, 1989 Nicole Israël +7 more
openalex +1 more source
Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications
Advanced Intelligent Systems, EarlyView.Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu +4 more
wiley +1 more source
Several antigenic determinants exposed on the gp120 moiety of HIV-1 gp160 are hidden on the mature gp120. [PDF]
, 1989 Clotilde Thiriart +9 more
openalex +1 more source
Transcription‐independent functions of p53 in DNA repair pathway selection
BioEssays, Volume 45, Issue 1, January 2023., 2023 Transcription‐independent early recruitment and PARylation of p53 at DNA damage sites promotes the recruitment of particular repair factors (e.g. DDB1 and 53BP1) and thereby tipping the balance of repair pathway selection. Abstract Recently discovered transcription‐independent features of p53 involve the choice of DNA damage repair pathway after ...
Yu‐Hsiu Wang, Michael P. Sheetz
wiley +1 more source
Second European Round Table on the Future Management of HIV
Journal of Virus Eradication, 2015 The Second European Round Table on the Future Management of HIV took place in Barcelona, 10–11 October 2014 and focused on the HIV-1 reservoir, strategies for HIV cure and primary HIV infection (PHI).
Casper Rokx +14 more
doaj
Ongoing Vaccine and Monoclonal Antibody HIV Prevention Efficacy Trials and Considerations for Sequel Efficacy Trial Designs [PDF]
arXiv, 2019 Four randomized placebo-controlled efficacy trials of a candidate vaccine or passively infused monoclonal antibody for prevention of HIV-1 infection are underway (HVTN 702 in South African men and women; HVTN 705 in sub-Saharan African women; HVTN 703/HPTN 081 in sub-Saharan African women; HVTN 704/HPTN 085 in U.S., Peruvian, Brazilian, and Swiss men ...
arxiv
Asian Journal of Organic Chemistry, EarlyView.Azide‐tethered iodonium ylides under copper catalysis generate metallocarbenes that undergo intramolecular trapping by the azide moiety and generate a reactive C‐acylimine, effectively coupling two nucleophilic centers. This intermediate can be trapped by a wide range of nucleophiles or 1,3‐dienes producing complex indolin‐3‐ones and ...
Israel Najar Guerrero +2 more
wiley +1 more source