Results 201 to 210 of about 658,368 (320)

Severe myelosuppression and alopecia after thiopurine initiation in a patient with NUDT15 deficiency

British Journal of Clinical Pharmacology, EarlyView.
Thiopurines are a class of immunosuppressant and antineoplastic agents. They are widely used in the treatment of inflammatory bowel disease, haematological malignancies and autoimmune diseases, but can cause significant toxicity. Inherited gene mutations are now recognized as independent risk factors for severe adverse drug reactions to thiopurines ...
Annie Siyu Wu, Lee Mozessohn, Richard B. Kim, Jonathan S. Zipursky   +3 more
wiley   +1 more source

HIV-1 replication is controlled at the level of T cell activation and proviral integration.

, 1990
Mario Stevenson, Trevor L. Stanwick, Michael P. Dempsey, C.A. Lamonica   +3 more
openalex   +1 more source

Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines [PDF]

, 1994
Annamari Ranki, Anssi Lagerstedt, Vladimir Ovod, Einari Aavik, Kai Krohn   +4 more
openalex   +1 more source

Impact of chromatin on HIV-1 latency: a multi-dimensional perspective. [PDF]

Epigenetics Chromatin
Jones JE, Gunderson CE, Wigdahl B, Nonnemacher MR.   +3 more
europepmc   +1 more source

Penetrating aortic ulceration as a initial presentation of Erdheim‐Chester Disease

Arthritis &Rheumatology, Accepted Article.
Jerome Razanamahery, Bernard Bonnotte
wiley   +1 more source

Safety of sulfamethoxazole–trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta‐analysis with active comparator disproportionality analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra, Lujain Ez Eddin, Fatemeh Ahmadi, Atefeh Jafari, Flory T. Muanda   +4 more
wiley   +1 more source

A cytotoxic survey on 2‐amino‐1H‐imidazol based synthetic marine sponge alkaloid analogues

Drug Development Research, Volume 83, Issue 8, Page 1906-1922, December 2022., 2022
Abstract Here, we describe the synthesis and biologic activity evaluation of 20 novel synthetic marine sponge alkaloid analogues with 2‐amino‐1H‐imidazol (2‐AI) core. Cytotoxicity was tested on murine 4T1 breast cancer, A549 human lung cancer, and HL‐60 human myeloid leukemia cells by the resazurin assay.
Nikolett Gémes, Zsófia Makra, Patrícia Neuperger, Enikő Szabó, József Á. Balog, Lili Borbála Flink, Beáta Kari, László Hackler Jr, László. G. Puskás, Iván Kanizsai, Gábor J. Szebeni   +10 more
wiley   +1 more source

Quiescent T Lymphocytes as an Inducible Virus Reservoir in HIV-1 Infection

, 1991
Michael Bukrinsky, Trevor L. Stanwick, Michael P. Dempsey, Mario Stevenson   +3 more
openalex   +2 more sources

The majority of neutralizing Abs in HIV-1-infected patients recognize linear V3 loop sequences. Studies using HIV-1MN multiple antigenic peptides. [PDF]

, 1994
Thorsten U. Vogel, Reinhard Kurth, Steve Norley   +2 more
openalex   +1 more source

Heat shock protein 90 is a chaperone regulator of HIV-1 latency. [PDF]

PLoS Pathog
Noorsaeed S, AlBurtamani N, Rokan A, Fassati A.   +3 more
europepmc   +1 more source