Results 221 to 230 of about 707,804 (298)

Tracking the protein conformational motions driving HIV-1 membrane fusion. [PDF]

Sci Rep
Unarta IC, Crotzer S, Gnanakaran S.
europepmc   +1 more source

CuH‐Catalyzed Asymmetric Desymmetrization of Cyclobutenes via Stereodivergent Hydroamination

ChemistryEurope, EarlyView.
The CuH‐catalyzed stereodivergent hydroamination through asymmetric desymmetrization of cyclobutenes has been achieved, yielding a range of trisubstituted aminocyclobutanes with excellent results. A series of subsequent transformations, including the first asymmetric synthesis of two pharmaceutically active molecules, have been realized, and density ...
Xiang Lei, Peng Luo, Shouang Lan, Wennan Dong, Chao Xu, Jinggong Liu, Shuang Yang, Qi Zhang, Xinqiang Fang   +8 more
wiley   +1 more source

Endocervix exhibits greater susceptibility to HIV-1 infection compared to ectocervix following ex vivo exposure to Transmitted/Founder HIV-1 variants. [PDF]

PLoS One
Langat R, McRaven MD, Lorenzo-Redondo R, Muhomah T, Carias AM, Arif MS, Akiso MM, Mureithi M, Anzala O, Gilmour J, Joseph S, Hope TJ.   +11 more
europepmc   +1 more source

Potential Influence of More-Sensitive HIV-1 Load Detection by the new Roche Cobas AmpliPrep/Cobas TaqMan Version 2.0 Assay on Clinical Management of HIV-Positive Pregnant Women

, 2010
Mark de Boer, Els Wessels, Eric C. J. Claas, Frank P. Kroon   +3 more
openalex   +2 more sources

Synthetic Cathepsin B Sensitive Adjuvant‐Peptide Conjugates to Target Intracellular Toll‐Like Receptors 7 and 8

ChemistryEurope, EarlyView.
Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn, Giulia Castello, Nico J. Meeuwenoord, Martijn Verdoes, Jeroen D. C. Codée, Ferry Ossendorp, Dmitri V. Filippov   +6 more
wiley   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Anti-HIV-1 Activity of the Integrase Strand Transfer Inhibitor ACC017. [PDF]

Viruses
Ma MD, Luo RH, Li CY, Huang GC, Long XY, He FY, Yang LM, Fu HL, Zheng YT.   +8 more
europepmc   +1 more source

Recent Advances in Chemical Probing Strategies for RNA Structure Determination in Vivo

Chemistry – A European Journal, EarlyView.
This Review illustrates how structural probes combined with advanced sequencing technologies are revolutionizing our ability to map RNA structures and interactions within living cells. It highlights the development of innovative strategies tailored to probe RNA structures in particular biological contexts.
Maryana Yarshova, Jieyu Zhao, Chun Kit Kwok   +2 more
wiley   +1 more source

Ageing with HIV-1: immunological challenges for effective vaccination. [PDF]

Immun Ageing
Saint-Charles P, Didierlaurent AM, Appay V.   +2 more
europepmc   +1 more source