Results 241 to 250 of about 31,026,669 (309)

Harmonizing HIV-1 RNA laboratory measurements in a longitudinal cohort collaboration. [PDF]

Am J Epidemiol
Lee JS, Humes E, Haw NJL, Hogan B, Zheng C, Coburn S, Lesko CR, Lang R, Gill MJ, Horberg M, Silverberg MJ, Palella FJ, Delaney JA, Rebeiro PF, Sterling T, Rodriguez-Barradas M, Marconi VC, Yendewa GA, Klein MB, Moore R, Althoff KN.   +20 more
europepmc   +1 more source

Evaluating Vaginal Microbiome Effects on Antiretroviral Exposure in the Female Genital Tract Using Pharmacometric and Machine Learning Approaches

Clinical Pharmacology &Therapeutics, EarlyView.
Antiretroviral pre‐exposure prophylaxis (PrEP) is less effective in women than expected, partly because drug exposure within the female genital tract is variable and may be influenced by the vaginal microbiome. We developed an integrated pharmacometrics and machine learning framework to evaluate associations between vaginal microbiome composition and ...
Diqin Yan, Lindsey B. Collins, Christopher Staley, Flavia Kiweewa Matovu, Pamala Jacobson, Melanie Nicol, Shen Cheng   +6 more
wiley   +1 more source

Differential selectivity of microglia and astrocytes in HIV-1 gp120-induced synaptic pruning. [PDF]

Brain
Watson ZT, Valdebenito-Silva S, Spurgat M, Ru W, Zheng J, Maurelli MK, Liang Y, Yuan S, Eugenin E, Tang SJ.   +9 more
europepmc   +1 more source

Unbound Intrinsic Formation Clearance of 6β‐Hydroxycortisol Is a Useful Biomarker of CYP3A4 Activity during Pregnancy

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy results in multiple physiological changes that impact drug disposition. For example, hepatic CYP3A activity and renal transporter‐mediated clearance increase in late pregnancy, but the time course of these changes across pregnancy is not known.
Aurora K Authement, Mary F Hebert, Emily E Fay, Nina Isoherranen   +3 more
wiley   +1 more source

Late-stage Diversification of HIV-1 Protease Inhibitor via SuFEx Click Chemistry. [PDF]

Synthesis (Stuttg)
Khanal B, Yamanushkin P, Gold B.
europepmc   +1 more source

Family's socioeconomic and demographic factors on elements of children's dental and oral health: A scoping review

Clinical and Experimental Dental Research, EarlyView.
Abstract Background Family plays a significant role in children's dental and oral health (DOH) elements, such as children's DOH knowledge and practice, the development of children's dental fear and anxiety (DFA), children's dental visits, and children's DOH status.
Wisnu Fadila, Mugia B. Rahardja, Puguh Prasetyoputra, Anne A. Suwargiani, Yanu E. Prasetyo, Eriska Riyanti   +5 more
wiley   +1 more source

A novel synergistic phycobiliprotein combination against HIV-1 shows potent antiviral activity. [PDF]

AMB Express
Jadaun P, Harshithkumar R, Khan I, Dass D, Wakchaure P, Kadam R, More A, Dhotre K, Siddiqi NJ, Alsadoun A, Malik A, Nandi SS, Nema V, Khan AA, Mukherjee A.   +14 more
europepmc   +1 more source

The Influence of Ethical Ideologies on Corporate Social Performance in Small and Medium‐Sized Enterprises in the United Kingdom

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Research addressing the microfoundations of corporate social performance (CSP) in small and medium‐sized enterprises (SMEs) remains sparse. This paper aims to investigate how SME managers' ethical ideology affects CSP and examines the mediating role of their CSR orientation (CSRO): economic, legal, ethical, and philanthropic.
Sarah Mohammad Suleiman Alsyoof, Vasa László, Tamás Sneider   +2 more
wiley   +1 more source

Structural determination of the HIV-1 Variable Region 3 epitope of antibody 19b. [PDF]

J Virol
Fetics SK, Mehta A, Nicely NI, Chen C-H(, Lindenberger J, Acharya P.   +5 more
europepmc   +1 more source

Design, Synthesis, In Silico Studies, and HIV-1 RT Inhibitory Activity of 1,3-Oxazolidine Pyrimidine Nucleoside Analogues. [PDF]

Chem Biodivers
Sriharsha SN, Mohamed ZM, Mahmood AAR, Sangi SMA, Shaik S, Nagaraja S, Kumari S, Thirunavukkarasu V, Sreenivasalu PK, Islam M, Chohan MS, Biradar MS.   +11 more
europepmc   +1 more source