Results 231 to 240 of about 24,860,034 (345)

HIV-1 binds dynein directly to hijack microtubule transport machinery. [PDF]

Sci Adv
Badieyan S, Lichon D, Keceli SK, Andreas MP, Gillies JP, Peng W, Shi J, DeSantis ME, Aiken CR, Böcking T, Giessen TW, Campbell EM, Cianfrocco MA.   +12 more
europepmc   +1 more source

Severe Vasoplegic Syndrome Treated with Angiotensin II and Hemoadsorption Therapy after Cardiac Surgery

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Vasoplegic syndrome (VS) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB). The main pathophysiology mechanism of VS includes a systemic inflammatory response syndrome due to surgical trauma, release of pro‐inflammatory mediators caused by blood contact with foreign surfaces of heart‐lung machine (pump and tubing)
Matteo Lucchelli, Davide Tommaso Andreis, Mattia Gomarasca, Giovanni Mistraletti   +3 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

The Confluence of HIV-1 and HIV-2: Implications for Disease Progression and Insights for Therapy. [PDF]

Int J Microbiol
Magomere E, Olwal CO, Tetteh BE, Appeaning M, Ndung'u T, Kyei GB, Quashie PK.   +6 more
europepmc   +1 more source

In Vitro Modification of Human Immunodeficiency Virus Type 1 (HIV‐1) Infectivity by the U937 Cells [PDF]

, 1993
Mohamed A. El‐Farrash, Takao Masuda, Marcelo J. Kuroda, Shinji Harada   +3 more
openalex   +1 more source

Inhibition of the Clathrin Terminal Domain—Amphiphysin Protein–Protein Interaction. Probing the Pitstop 2 Aromatic Moiety

ChemMedChem, EarlyView.
Pitstop 2 binds to the clathrin terminal domain. This work explores the nature of the benzylidene moiety, R. The synthesis of 56 novel analogues reveals enhanced potency of a multiple analogues, with catechol‐free 2,3‐dihydroxybenzo[b][1,4]dioxone (54) returning a 1.2 μm IC50, ca 10‐fold more active than Pitstop 2. Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)
Kate Prichard, Mark J Robertson, Ngoc Chau, Jing Xue, Martin Neuenschwander, Uwe Fink, Andre Horatscheck, Marc Nazare, Phillip J Robinson, Volker Haucke, Adam McCluskey   +10 more
wiley   +1 more source

CARD8 inflammasome activation during HIV-1 cell-to-cell transmission. [PDF]

Elife
Kulsuptrakul J, Emerman M, Mitchell PS.
europepmc   +1 more source

Deoxynucleotide polymerization by HIV-1 reverse transcriptase is terminated by site-specific styrene oxide adducts after translesion synthesis.

, 1994
Gary J. Latham, R. Stephen Lloyd
openalex   +1 more source

HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation

Nature, 2019
Ravindra K. Gupta, Sultan Abdul-Jawad, Laura E. McCoy, H. Mok, D. Peppa, M. Salgado, J. Martinez-Picado, M. Nijhuis, A. Wensing, Helen H. Lee, P. Grant, E. Nastouli, J. Lambert, M. Pace, F. Salasc, C. Monit, A. Innes, L. Muir, L. Waters, J. Frater, A. Lever, S. Edwards, I. Gabriel, E. Olavarría   +23 more
semanticscholar   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

Chemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui, Tien‐Hung Lan, Yubin Zhou   +2 more
wiley   +1 more source