Results 111 to 120 of about 30,382,849 (226)
EBioMedicine, 2016 Persistence of latent, replication-competent Human Immunodeficiency Virus type 1 (HIV-1) provirus is the main impediment towards a cure for HIV/AIDS (Acquired Immune Deficiency Syndrome). Therefore, different therapeutic strategies to eliminate the viral
Lenard S. Vranckx +12 more
doaj +1 more source
Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 1037-1049, October 2026.ABSTRACT Background Antiretroviral therapy has transformed HIV into a chronic condition, yet cardiac injury remains a major issue. Purpose To assess the ability of cardiac MR imaging markers to predict cardiac injury and disease progression in HIV‐infected individuals. Study Type Prospective.
Chunyan Deng +5 more
wiley +1 more source
Frontiers in Microbiology, 2019 The human immunodeficiency virus type 1 (HIV-1) has several proteins of therapeutic importance, many of which are currently used as drug targets in antiretroviral therapy. Among these proteins is the integrase, which is responsible for the integration of
Lucas de Almeida Machado +2 more
doaj +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 10, October 2026.ABSTRACT Characterizing dolutegravir penetration into the central nervous system is important for optimizing human immunodeficiency virus treatment outcomes, yet population‐specific pharmacokinetic data describing cerebrospinal fluid disposition and equilibration kinetics remain lacking.
Mohammed W. Ali +8 more
wiley +1 more source
Aging Cell, Volume 25, Issue 10, October 2026.Thymic involution, the age‐related replacement of thymic soft tissue by fat, has been linked to immunosenescence and chronic inflammation. Whether HIV infection affects thymic involution remains unclear. We found that people with HIV on long‐term antiretroviral therapy had more thymic tissue than controls, indicating less thymic involution. More thymic
Manon C. Vanbellinghen +15 more
wiley +1 more source
SIEDY Diagnostic Accuracy in Assessing Erectile Dysfunction in Young Men Living With HIV
Andrology, Volume 14, Issue 7, Page 2290-2296, October 2026.ABSTRACT Background Erectile dysfunction (ED) is a multidimensional condition commonly affecting men living with HIV. The structured interview of erectile dysfunction (SIEDY) is the only validated tool assessing organic, relational, and psychological factors contributing to ED, while dynamic penile color Doppler ultrasound (dPCDU) is a reliable method ...
Giorgio Tiecco +10 more
wiley +1 more source
Validation of replicative phenotyping to detect and assign HIV-1 resistance in clinical specimens [PDF]
, 2009 The ability of HIV-1 to develop resistance to antiretroviral drugs has limited the overall efficacy of combination therapy to suppress viral replication.
Louvel, Séverine
core +1 more source
Characterization and structural analysis of HIV-1 integrase conservation
, 2009 The HIV-1 integrase, responsible for the chromosomal integration of the newly synthesized double-stranded viral DNA into the host genomic DNA, represents a new and important target of potential clinical relevance.
PERNO, CARLO FEDERICO +5 more
core +1 more source
HIV Medicine, Volume 27, Issue 10, Page 1650-1662, October 2026.Abstract Objectives We aimed to determine the prevalence of metabolic disorders, liver steatosis and metabolic dysfunction‐associated steatotic liver disease (MASLD) in a cohort of middle‐aged women with HIV (WoWH) and to explore associations between liver steatosis, visceral fat depots and carotid atherosclerosis.
Mariacristina Poliseno +13 more
wiley +1 more source
Peptide HIV-1 Integrase Inhibitors from HIV-1 Gene Products
, 2016 Anti-HIV peptides with inhibitory activity against HIV-1 integrase (IN) have been found in overlapping peptide libraries derived from HIV-1 gene products.
Hirokazu Tamamura (1490866) +21 more
core +1 more source