Results 211 to 220 of about 120,919 (245)

Equity and Access in HIV Prevention: Addressing Global Disparities in PrEP Use Among Men Who Have Sex With Men Population. [PDF]

Am J Mens Health
Li S, Chan ASW.
europepmc   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

PrEP and Contraceptive Persistence Among Young Women Receiving Sexual and Reproductive Health Services Through Hair Salons in South Africa. [PDF]

J Acquir Immune Defic Syndr
Bassett IV, Yan J, Govere S, Johnson LS, Shezi S, Ngcobo LM, Sagar S, Sagar S, Jarolimova J, Zionts D, Khumalo A, Zwane PG, Dube N, Psaros C, Parker RA.   +14 more
europepmc   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source

PrEP uptake, persistence, and patterns of choice dynamics between oral and long-acting injectable with cabotegravir among sexually and gender-diverse adolescents in Brazil: a multisite cohort implementation study. [PDF]

Lancet Reg Health Am
Magno L, Leite BO, Zeballos D, Soares F, Dezanet L, Westin M, Tupinambás U, Greco D, Massa P, Grangeiro A, Dourado I, PrEP15-19 Choices Study.   +11 more
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

HIV Reservoirs Across Multiple Tissues: From Heterogeneous Mechanisms to Therapeutic Targeting. [PDF]

Microorganisms
Wu YL, Lan GW, Jiang LY, Chen X.
europepmc   +1 more source

From Mask to Bed: Protective Barrier Containment and Rethinking the Prevention of Pathogen Transmission

Microbiota Medicine Research, EarlyView.
Quan Wen, Sheng Zhang, Qian Wang, Yuan Wu, Wei Hong, Juan Liao, Hon Ho Yu, Furu Wang, Yongzhan Nie, Faming Zhang   +9 more
wiley   +1 more source

RNA‐DNA Fusomer Fibers With Customizable Physicochemical, Mechanical, and Biological Properties for Next‐Generation Therapeutics

Small, EarlyView.
ABSTRACT We introduce RNA‐DNA fusomers, a new class of chemically synthesized oligonucleotides that combine the versatile properties of RNA and DNA within a single sequence and self‐assemble into higher‐order functional structures via a simple one‐pot annealing reaction.
Yasmine Radwan, Laura P. Rebolledo, Yelixza I. Avila, Elizabeth Skelly, Lauren Rackley, Julio Navas Hernandez, Renata de Freitas Saito, Laxmi K. Pandey, Hemani Chhabra, Alexander J. Lushnikov, Tatiane Katsue Furuya, Ana Luiza Lomba, Da Shi, Edward Cedrone, Ian Marriott, Morgan R. Chandler, Meni Wanunu, Aleksei Aksimentiev, Alexey V. Krasnoslobodtsev, Roger Chammas, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Virus-directed CAR immunotherapies for chronic HBV and HIV: a systematic synthesis of preclinical and early clinical evidences. [PDF]

Front Med (Lausanne)
Sleman S, Ameen MB, Abid OI, Abdullah BJ, Abass ZA.   +4 more
europepmc   +1 more source