Results 151 to 160 of about 178,048 (244)

Retracted: Effect of HIV-1 Protease Inhibitor on IL-18 and IL-1β in Rats with Insulinoma. [PDF]

Dis Markers, 2023
Markers D.
europepmc   +1 more source

Low‐Barrier Fibrosis Screening in Hepatitis C Treatment: The Decompensated Cirrhosis in Hepatitis C Evaluation Questionnaire

Journal of Viral Hepatitis, Volume 33, Issue 6, June 2026.
ABSTRACT Achieving hepatitis C virus (HCV) elimination requires innovative paradigms that overcome barriers to treatment, such as requiring pre‐treatment elastography or phlebotomy‐based fibrosis assessment. To identify patients at low risk of advanced fibrosis or decompensated cirrhosis within our HCV treatment programme, we developed and ...
Hunter Spencer, Barbara Brumbach, Anna Geduldig, Lisa Nelson, Andrew Seaman   +4 more
wiley   +1 more source

Mutational scan of self-cleavage by HIV-1 protease provides new views of a conformationally dynamic mechanism. [PDF]

J Virol
Nachum GS, Boucher JI, Flynn JM, Quansah P, Nachum S, Bolon DNA.   +5 more
europepmc   +1 more source

Inhibition of HIV-1 Protease by a Boronic Acid with High Oxidative Stability. [PDF]

ACS Med Chem Lett, 2023
Graham BJ, Windsor IW, Raines RT.
europepmc   +1 more source

PWO proteins are associated with PRC2 since their emergence in vascular plants

New Phytologist, Volume 250, Issue 6, Page 4002-4021, June 2026.
Summary The Polycomb repressive complex 2 (PRC2), a conserved histone methyltransferase complex, plays a central role in transcriptional silencing across eukaryotes. Here, we investigate the evolution of PWWP‐DOMAIN INTERACTORS OF POLYCOMBS (PWOs), which interact with PRC2, and examine the conservation of the PWOs‐PRC2 interaction across plant ...
Ahamed Khan, Saqlain Haider, Abdoallah Sharaf, Alžbeta Kusová, Jan Skalák, Claire Jourdain, Martin Rennie, Petra Procházková Schrumpfová, Jan Hejátko, Daniel Schubert, Sara Farrona, Iva Mozgová   +11 more
wiley   +1 more source

Residue-Level Affinity Decomposition via Quantum Electron Density: A Multivariable Framework Applied to HIV-1 Protease Inhibitors. [PDF]

J Phys Chem B
Gutiérrez-Flores J, Padilla-Bernal G, Sánchez-Juárez C, Méndez-Orduña DM, Serrano Medina J, García-Gutiérrez P, Zubillaga RA, Vargas R.   +7 more
europepmc   +1 more source

Exact reaction coordinates for flap opening in HIV-1 protease. [PDF]

Proc Natl Acad Sci U S A, 2022
Wu S, Li H, Ma A.
europepmc   +1 more source

Post‐surgery level of circulating DNA in stage III colon cancer patients: Impact on the reliability of minimal residual disease detection

International Journal of Cancer, Volume 158, Issue 10, Page 2771-2783, 15 May 2026.
What's New? Circulating nuclear DNA (cir‐nDNA)‐based assessment of minimal residual disease (MRD) offers powerful post‐surgery prognostic insight for stage III colon cancer (CC). Sparse knowledge of post‐surgical variations and origins in cir‐nDNA, however, has limited its clinical application.
Andrei Kudriavtsev, Saidi Daoud, Catalina Isabel Cofre Muñoz, Alexia Mirandola, Ekaterina Pisareva, Javier Gonzalo Ruiz, Marco Macagno, Nadia Saoudi Gonzalez, Evelyne Crapez, Marc Ychou, Ramon Salazar Soler, Elisabetta Fenocchio, Paula X. Fernandez Calotti, Thibault Mazard, Cristina Santos Vivas, Elena Elez, Federica Di Nicolantonio, Alain R. Thierry   +17 more
wiley   +1 more source

Designing Potent HIV‑1 Protease Inhibitors Using Machine Learning and QSAR Approaches. [PDF]

ACS Omega
Ali S, Dwi Putra I, Chuntakaruk H, Wolschann P, Maitarad P, Rungrotmongkol T, Hannongbua S.   +6 more
europepmc   +1 more source

Evolving Mutational Buildup in HIV-1 Protease Shifts Conformational Dynamics to Gain Drug Resistance. [PDF]

J Chem Inf Model, 2023
Souffrant M, Yao XQ, Hamelberg D.
europepmc   +1 more source