Results 191 to 200 of about 726,640 (329)

Physiologically based pharmacokinetic model combined with a clinical lactation study to determine doravirine concentrations in human breastmilk

British Journal of Clinical Pharmacology, EarlyView.
Aims To determine breastmilk concentrations of doravirine via PBPK modelling in combination with a clinical lactation study. As women living with HIV are not able to cease antiretroviral therapy during lactation, it is necessary to establish drug transfer into breastmilk to determine exposure of the infant to antiretroviral drugs and potential risk of ...
Lena van der Wekken‐Pas, David Burger, Rick Greupink, Angela Colbers   +3 more
wiley   +1 more source

Under the Radar: Immune Evasion, Pathogenesis and Control of HIV Infection. [PDF]

Int J Mol Sci
Tarrés-Freixas F, Trinité B, Carrillo J, Blanco J.   +3 more
europepmc   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Cardiac mass in a patient with HIV infection: A case report and literature review. [PDF]

Exp Ther Med
Gradinaru A, Colita A, Muraretu I, Bajdechi M, Mihailescu A, Saguna C, Roxana R, Gurghean AL.   +7 more
europepmc   +1 more source

State of Alaska epidemiology bulletin: HIV infection-Alaska 1996: Part 3

, 1997

openalex   +1 more source

Expert opinion: Seeking truth through inquiry: A discussion on the online news from Science on November 21, “Exclusive: CDC to end all monkey research”

Animal Models and Experimental Medicine, EarlyView.
Zhiguang Xiang, Chuan Qin
wiley   +1 more source

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe, Lufina Tsirizani, Buyisile Mkhize, Lubbe Wiesner, Gary Maartens, Francesca Conradie, Richard Court, Marian Loveday, Catriona Waitt, Paolo Denti   +9 more
wiley   +1 more source

HIV infection during pregnancy: antiretroviral therapy and the associations with migrant status. [PDF]

BMC Public Health
Liu Z, Dong K, Sun M, Lin D, Chen Y, Zhang X.   +5 more
europepmc   +1 more source

Predicting COVID-19 outcomes in patients at advanced stages of HIV infection: a model-based approach [PDF]

Anna E. Tsygankova, Vladimir Chulanov, A. N. Gerasimov, E. V Volchkova, Anton A. Privalenko, Viktoriya A. Bakhtina, Vladimir A. Khabudaev, Dina Baimukhambetova   +7 more
openalex   +1 more source

Pharmacokinetic modelling of intravenous immunoglobulin in children with primary immunodeficiencies and secondary antibody deficiencies

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng, Zhong Hui Huang, Austen Worth, Claire Booth, Joseph F. Standing   +4 more
wiley   +1 more source