Results 171 to 180 of about 2,775,555 (408)
Application of Radial Basis Network Model for HIV/AIDs Regimen Specifications [PDF]
HIV/AIDs Regimen specification one of many problems for which bioinformaticians have implemented and trained machine learning methods such as neural networks. Predicting HIV resistance would be much easier, but unfortunately we rarely have enough structural information available to train a neural network.
arxiv
New Transferrin Receptor‐Targeting Conjugate Effectively Delivers DNA to Mouse Brain
We present a novel RNA aptamer targeting the transferrin receptor (TfR), conjugated with DSPE lipid, which achieves remarkably efficient brain uptake, reaching brain‐to‐serum ratios as high as 6.5. Through fluorescence imaging and polymerase‐chain reaction analyses, we verify that this new conjugate successfully delivers a substantial amount of DNA ...
Min‐sun Song+8 more
wiley +2 more sources
ABSTRACT This qualitative study aimed to understand how migration experiences shape wellbeing and quality of life (QoL) for Asian‐born men who have sex with men (MSM) who are living with HIV in Australia, and to identify relevant support needs. Drawing from intersectionality theory, this paper reports findings from semi‐structured interviews with Asian‐
Thomas Norman+9 more
wiley +1 more source
This study interpreted the differential profiles of cervicovaginal microbiota and CSTs between HC women and HPV16‐infected women with CIN I, CIN II/III or SCC. The relationship between HPV16 clearance and cervicovaginal microbiota composition in each disease stage before and after clinical treatments was also established.
Chao Li+3 more
wiley +1 more source
This study designs an anchor peptide‐based immobilization strategy to expand the application of Pickering emulsion to glycosyltransferases (GTs) for the first time, addressing low conversion challenge in aqueous solutions. The glycosylation Pickering emulsion achieved more than 90% conversion of natural product glycosides with high recyclability ...
Peng Zhang+5 more
wiley +2 more sources
Perceptions of HIV-positive kidney donations to HIV-positive recipients [PDF]
BACKGROUND: Kidney transplantation is the preferred standard of care for patients who have both end stage renal disease (ESRD) and human immunodeficiency virus (HIV) infection.
Stomel, Julie
core
MiR‐221‐3p Attenuates IL‐33‐Induced Mast Cell Cytokine Expression by Targeting KIT
ABSTRACT Background Mast cells (MCs) are involved in type 2 inflammation in chronic rhinosinusitis with nasal polyps (CRSwNP), which depends on interleukin (IL)‐33 stimulation. MiR‐221 is reported to be an important regulator of MCs, and miR‐221‐3p can be expressed in CRSwNP. However, the role of miR‐221‐3p in CRSwNP is unclear. Methods Ethmoid tissues
Ruowu Liu+11 more
wiley +1 more source
Antifungal Compounds from the Leaves of Rhynchosia minima
Abstract Rhynchosia minima, commonly known as jumby bean, is used as a remedy for respiratory ailments in various parts of the world. It is also used by South African traditional healers to treat heart or chest pain. This study aimed to investigate the bioactive constituents of the leaf extracts of R.
Adetola H. Adewole+4 more
wiley +1 more source
Ending AIDS in Gabon: How long will it take? How much will it cost? [PDF]
The prevalence of HIV in West Africa is lower than elsewhere in Africa but Gabon has one of the highest rates of HIV in that region. Gabon has a small population and a high per capita gross domestic product making it an ideal place to carry out a programme of early treatment for HIV.
arxiv
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri+10 more
wiley +1 more source